FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022022988> ?p ?o ?g. }

• W2022022988 endingPage "154" @default.
• W2022022988 startingPage "149" @default.
• W2022022988 abstract "Resistensi methicillin resistant Staphylococcus aureus (MRSA) terhadap berbagai antimikrob terutama didasari adanya insersi mobile genetic elements yang disebut Staphylococcal cassette chromosome mec (SCCmec) pada kromosom Staphylococcus aureus. SCCmec tersusun atas gen rekombinase (ccr), gen kompleks mec, gen resisten tambahan, dan insertion sequences. Struktur gen rekombinase memungkinkan SCCmec dapat berpindah dari satu bakteri ke bakteri lainnya. Identifikasi dan analisis SCCmec sangat diperlukan untuk mengetahui dasar genetik resistensi dan memperkirakan penyebaran bakteri ini. Penelitian ini bertujuan menganalisis tipe SCCmec dan hubungannya dengan pola kepekaan MRSA terhadap berbagai antimikrob. Penelitian ini adalah penelitian observasional analitik dengan pendekatan molekuler berupa typing SCCmec dan uji kepekaan terhadap antimikrob, periode Juli–Desember 2007. Pembiakan dan identifikasi 45 isolat MRSA dilakukan di Departemen Mikrobiologi Fakultas Kedokteran Unpad, sedangkan penentuan gen mecA dan PCR multipleks SCCmec dilakukan di Fakultas Kedokteran Universitas Sriwijaya, Palembang. Seluruh 45 isolat MRSA yang diteliti, dipastikan memiliki gen mecA. Analisis PCR multipleks menunjukkan 40 isolat memiliki SCCmec tipe III dan 5 isolat memiliki tipe IV. Semua isolat dengan SCCmec tipe III bersifat multiresisten, sedangkan tipe IV tidak bersifat multiresisten. Dapat disimpulkan bahwa MRSA dengan genotip SCCmec tipe III berhubungan, sedangkan tipe IV tidak berhubungan dengan sifat multiresisten. [ MKB . 2010;42(4):149–54]. Kata kunci : Methicillin resistant Staphylococcus aureu s(MRSA) , pola kepekaan, tipe SCCmec Staphylococcal Casette Chromosome mec (SCCmec) Type Analysis of Methicillin Resistant Staphylococcus aureus (MRSA) Isolates Resistance of methicillin resistant Staphylococcus aureus (MRSA) were based mainly on insertion of mobile genetic elements namely Staphylococcal cassette chromosome mec (SCCmec) in the chromosome of Staphylococcus aureus. SCCmec consists of recombinase genes (ccr), mec genes complex, additional resistance genes, and insertion sequences. Recombinase genes structure mediates transfer of SCCmec from one bacteria to another. Identification of SCCmec is very important to know basic genetic resistance and to predict spreading of MRSA. The aim of this research was to analyze SCCmec type and antimicrobial susceptibility patterns. The design of this study was observational analytic study by typing SCCmec and antimicrobial susceptibility testing on July– December 2007. Isolation and identification of 45 MRSA isolates was performed in the Department of Microbiology, Faculty of Medicine, University of Padjadjaran, whereas identification of mecA gene and typing of SCCmec by multiplex PCR was performed in the Department of Microbiology, Faculty of Medicine, Sriwijaya University, Palembang. The result showed that all isolates contained mecA gene. Multiplex PCR revealed that 40 MRSA isolates had SCCmec type III and 5 isolates with type IV. All SCCmec type III isolates were multiresistant and all of the type IV were not multiresistant. In conclusion, MRSA isolates with SCCmec type III was associated with multiresistant whereas type IV was not. [ MKB . 2010;42(4):149–54]. Key words : Methicillin resistant Staphylococcus aureus (MRSA), susceptibility patterns, type of SCCmec DOI: http://dx.doi.org/10.15395/mkb.v42n4.28" @default.
• W2022022988 created "2016-06-24" @default.
• W2022022988 creator A5037164556 @default.
• W2022022988 date "2010-01-01" @default.
• W2022022988 modified "2023-10-17" @default.
• W2022022988 title "Analisis Tipe Staphylococcal Cassette Chromosome mec (SCCmec) Isolat Methicillin Resistant Staphylococcus aureus (MRSA)" @default.
• W2022022988 cites W2029051951 @default.
• W2022022988 doi "https://doi.org/10.15395/mkb.v42n4.28" @default.
• W2022022988 hasPublicationYear "2010" @default.
• W2022022988 type Work @default.
• W2022022988 sameAs 2022022988 @default.
• W2022022988 citedByCount "3" @default.
• W2022022988 countsByYear W20220229882012 @default.
• W2022022988 countsByYear W20220229882018 @default.
• W2022022988 countsByYear W20220229882020 @default.
• W2022022988 crossrefType "journal-article" @default.
• W2022022988 hasAuthorship W2022022988A5037164556 @default.
• W2022022988 hasBestOaLocation W20220229881 @default.
• W2022022988 hasConcept C104317684 @default.
• W2022022988 hasConcept C11701158 @default.
• W2022022988 hasConcept C132533263 @default.
• W2022022988 hasConcept C22744801 @default.
• W2022022988 hasConcept C2776540679 @default.
• W2022022988 hasConcept C2777052132 @default.
• W2022022988 hasConcept C2779489039 @default.
• W2022022988 hasConcept C523546767 @default.
• W2022022988 hasConcept C54355233 @default.
• W2022022988 hasConcept C86803240 @default.
• W2022022988 hasConcept C89423630 @default.
• W2022022988 hasConceptScore W2022022988C104317684 @default.
• W2022022988 hasConceptScore W2022022988C11701158 @default.
• W2022022988 hasConceptScore W2022022988C132533263 @default.
• W2022022988 hasConceptScore W2022022988C22744801 @default.
• W2022022988 hasConceptScore W2022022988C2776540679 @default.
• W2022022988 hasConceptScore W2022022988C2777052132 @default.
• W2022022988 hasConceptScore W2022022988C2779489039 @default.
• W2022022988 hasConceptScore W2022022988C523546767 @default.
• W2022022988 hasConceptScore W2022022988C54355233 @default.
• W2022022988 hasConceptScore W2022022988C86803240 @default.
• W2022022988 hasConceptScore W2022022988C89423630 @default.
• W2022022988 hasIssue "4" @default.
• W2022022988 hasLocation W20220229881 @default.
• W2022022988 hasOpenAccess W2022022988 @default.
• W2022022988 hasPrimaryLocation W20220229881 @default.
• W2022022988 hasRelatedWork W1983792619 @default.
• W2022022988 hasRelatedWork W2010601134 @default.
• W2022022988 hasRelatedWork W2138528530 @default.
• W2022022988 hasRelatedWork W2151012051 @default.
• W2022022988 hasRelatedWork W2355110859 @default.
• W2022022988 hasRelatedWork W2918578413 @default.
• W2022022988 hasRelatedWork W2945025158 @default.
• W2022022988 hasRelatedWork W2969410483 @default.
• W2022022988 hasRelatedWork W760444094 @default.
• W2022022988 hasRelatedWork W2782018975 @default.
• W2022022988 hasVolume "42" @default.
• W2022022988 isParatext "false" @default.
• W2022022988 isRetracted "false" @default.
• W2022022988 magId "2022022988" @default.
• W2022022988 workType "article" @default.