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- W2022024100 abstract "The possible modulation by T4 DNA ligase of the DNA double-strand breaks produced by restriction endonucleases in living mammalian cells was studied. A clear decrease in the frequency of chromosomal aberrations was observed when T4 DNA ligase was included in the electroporation treatment along with restriction enzymes inducing either cohesive- or blunt-ends in DNA. The relative proportions of exchange-type aberrations were similar for both kinds of treatments (with and without ligase), which seems to suggest an error-free ligation by T4 DNA ligase." @default.
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- W2022024100 date "1995-01-01" @default.
- W2022024100 modified "2023-09-30" @default.
- W2022024100 title "T4 DNA ligase modulates chromosome damage induced by restriction endonucleases through an error-free process" @default.
- W2022024100 doi "https://doi.org/10.1093/mutage/10.5.399" @default.
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