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- W2022027322 abstract "In this questionnaire study, we examined responses to treatment, effect on lifestyle, beliefs of causation, and satisfaction with treatment method for Chronic Spontaneous Urticaria. 173 patients with CSU had been seen between 2003 and 2013. An autologous serum skin test (ASST) had been performed on 138 patients. 101 participants responded. Of the respondents, 80 were women and 21 men. The age range was 1 year to 81. The mean age was 36 years. The average duration of symptoms was 9.3 years. They included 40 patients who were ASST positive (M: F; 8:32) and 49 negative M:F; 12:37). 50 participants no longer had hives. Patients reported being most bothered by pruritus, disturbed sleep, anxiety and their physical appearance including facial swelling. Many (71.2%) had missed work or school because of the urticaria. Twenty-nine patients found antihistamines alone gave adequate relief of urticaria. Twenty ASST positive patients with severe uncontrollable hives were treated with intravenous immunoglobulin (IVIG). 85.0% of these patients had improved quality of life, with 13 of these patients now free of urticaria and no longer receiving IVIG. Three patients who did not benefit from IVIG did respond to methotrexate. No ASST negative patients received IVIG. Approximately 30% of patients found antihistamines gave effective control. Half the patients had been free of urticaria for at least 3 months. About 40% of patients with CSU had an autoimmune basis as assessed by the ASST and IVIG was a highly effective treatment for this group." @default.
- W2022027322 created "2016-06-24" @default.
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- W2022027322 date "2014-02-01" @default.
- W2022027322 modified "2023-09-27" @default.
- W2022027322 title "Chronic Spontaneous Urticaria-The Saskatchewan Experience and Questionnaire Survey" @default.
- W2022027322 doi "https://doi.org/10.1016/j.jaci.2013.12.456" @default.
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