FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022030660> ?p ?o ?g. }

• W2022030660 endingPage "692" @default.
• W2022030660 startingPage "686" @default.
• W2022030660 abstract "The presynaptic active zone (AZ) is a specialized site where neurotransmitter release occurs in a precisely regulated manner. The cytomatrix at the AZ (CAZ)-associated protein CAST and its family member ELKS form a large molecular complex at the AZ and regulate neurotransmitter release by binding other AZ proteins including Bassoon, Piccolo, Munc13-1, and RIM1. Here, yeast two-hybrid screening was used to identify Ligand-of-Numb Protein X (LNX) as a potential binding partner for CAST. LNX is an interactor of Numb and has four PDZ domains. CAST bound LNX both in vivo and in vitro. This binding required the COOH-terminus of CAST and the second PDZ domain of LNX. CAST and LNX were further colocalized with each other in a heterologous expression system, in which LNX was recruited to a Triton X-insoluble structure. Moreover, exogenously expressed LNX was partially colocalized with endogenous CAST in the axonal varicosities of cultured rat hippocampal neurons. These results suggest that CAST and LNX might form a protein complex in neurons." @default.
• W2022030660 created "2016-06-24" @default.
• W2022030660 creator A5003085960 @default.
• W2022030660 creator A5026096699 @default.
• W2022030660 creator A5033446220 @default.
• W2022030660 creator A5044532641 @default.
• W2022030660 creator A5065218492 @default.
• W2022030660 date "2007-03-01" @default.
• W2022030660 modified "2023-10-17" @default.
• W2022030660 title "The active zone protein CAST directly associates with Ligand-of-Numb protein X" @default.
• W2022030660 cites W1591639440 @default.
• W2022030660 cites W1944633888 @default.
• W2022030660 cites W1964731521 @default.
• W2022030660 cites W1970539905 @default.
• W2022030660 cites W1974020471 @default.
• W2022030660 cites W2008758031 @default.
• W2022030660 cites W2015752601 @default.
• W2022030660 cites W2024032585 @default.
• W2022030660 cites W2037914683 @default.
• W2022030660 cites W2040625259 @default.
• W2022030660 cites W2048162805 @default.
• W2022030660 cites W2049134173 @default.
• W2022030660 cites W2055804746 @default.
• W2022030660 cites W2055842243 @default.
• W2022030660 cites W2070755746 @default.
• W2022030660 cites W2076710726 @default.
• W2022030660 cites W2085850363 @default.
• W2022030660 cites W2088861631 @default.
• W2022030660 cites W2114775941 @default.
• W2022030660 cites W2136207368 @default.
• W2022030660 cites W2152139261 @default.
• W2022030660 cites W2162145655 @default.
• W2022030660 cites W2166556785 @default.
• W2022030660 cites W2166672567 @default.
• W2022030660 doi "https://doi.org/10.1016/j.bbrc.2007.01.036" @default.
• W2022030660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17257582" @default.
• W2022030660 hasPublicationYear "2007" @default.
• W2022030660 type Work @default.
• W2022030660 sameAs 2022030660 @default.
• W2022030660 citedByCount "17" @default.
• W2022030660 countsByYear W20220306602012 @default.
• W2022030660 countsByYear W20220306602013 @default.
• W2022030660 countsByYear W20220306602014 @default.
• W2022030660 countsByYear W20220306602016 @default.
• W2022030660 countsByYear W20220306602017 @default.
• W2022030660 countsByYear W20220306602018 @default.
• W2022030660 countsByYear W20220306602019 @default.
• W2022030660 crossrefType "journal-article" @default.
• W2022030660 hasAuthorship W2022030660A5003085960 @default.
• W2022030660 hasAuthorship W2022030660A5026096699 @default.
• W2022030660 hasAuthorship W2022030660A5033446220 @default.
• W2022030660 hasAuthorship W2022030660A5044532641 @default.
• W2022030660 hasAuthorship W2022030660A5065218492 @default.
• W2022030660 hasConcept C116569031 @default.
• W2022030660 hasConcept C148762608 @default.
• W2022030660 hasConcept C154428179 @default.
• W2022030660 hasConcept C169760540 @default.
• W2022030660 hasConcept C170493617 @default.
• W2022030660 hasConcept C185592680 @default.
• W2022030660 hasConcept C2776219046 @default.
• W2022030660 hasConcept C2776746469 @default.
• W2022030660 hasConcept C51639874 @default.
• W2022030660 hasConcept C529278444 @default.
• W2022030660 hasConcept C55493867 @default.
• W2022030660 hasConcept C86803240 @default.
• W2022030660 hasConcept C95444343 @default.
• W2022030660 hasConceptScore W2022030660C116569031 @default.
• W2022030660 hasConceptScore W2022030660C148762608 @default.
• W2022030660 hasConceptScore W2022030660C154428179 @default.
• W2022030660 hasConceptScore W2022030660C169760540 @default.
• W2022030660 hasConceptScore W2022030660C170493617 @default.
• W2022030660 hasConceptScore W2022030660C185592680 @default.
• W2022030660 hasConceptScore W2022030660C2776219046 @default.
• W2022030660 hasConceptScore W2022030660C2776746469 @default.
• W2022030660 hasConceptScore W2022030660C51639874 @default.
• W2022030660 hasConceptScore W2022030660C529278444 @default.
• W2022030660 hasConceptScore W2022030660C55493867 @default.
• W2022030660 hasConceptScore W2022030660C86803240 @default.
• W2022030660 hasConceptScore W2022030660C95444343 @default.
• W2022030660 hasFunder F4320320912 @default.
• W2022030660 hasIssue "3" @default.
• W2022030660 hasLocation W20220306601 @default.
• W2022030660 hasLocation W20220306602 @default.
• W2022030660 hasOpenAccess W2022030660 @default.
• W2022030660 hasPrimaryLocation W20220306601 @default.
• W2022030660 hasRelatedWork W191658356 @default.
• W2022030660 hasRelatedWork W2022030660 @default.
• W2022030660 hasRelatedWork W2037914683 @default.
• W2022030660 hasRelatedWork W2040625259 @default.
• W2022030660 hasRelatedWork W2055842243 @default.
• W2022030660 hasRelatedWork W2062994986 @default.
• W2022030660 hasRelatedWork W2068546264 @default.
• W2022030660 hasRelatedWork W2108539902 @default.
• W2022030660 hasRelatedWork W2152642445 @default.
• W2022030660 hasRelatedWork W2767790080 @default.
• W2022030660 hasVolume "354" @default.
• W2022030660 isParatext "false" @default.
• W2022030660 isRetracted "false" @default.

• next