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- W2022032861 endingPage "91" @default.
- W2022032861 startingPage "77" @default.
- W2022032861 abstract "Translocations and mutations in the core binding factor genes, RUNX1 or CBFB, are found in acute myeloid and lymphocytic leukemia, therapy-related myeloid leukemia, myelodysplastic syndrome, chronic myelomonocytic leukemia, and in familial platelet disorder with predisposition to acute myeloid leukemia. Here we review the biochemical and biological properties of the normal Runx1 protein, discuss the nature of RUNX1 mutations in myeloid leukemia, their prognostic significance, and the mutations that cooperate or co-exist with them in these various diseases." @default.
- W2022032861 created "2016-06-24" @default.
- W2022032861 creator A5017920497 @default.
- W2022032861 creator A5023287139 @default.
- W2022032861 date "2011-01-01" @default.
- W2022032861 modified "2023-09-27" @default.
- W2022032861 title "RUNX1 Mutations in Clonal Myeloid Disorders: From Conventional Cytogenetics to Next Generation Sequencing, A Story 40 Years in the Making" @default.
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