Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022033708> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2022033708 endingPage "546" @default.
- W2022033708 startingPage "541" @default.
- W2022033708 abstract "We examined the effects of 20 minutes' cerebral ischemia on cerebral microcirculatory responses to topical norepinephrine and systemic hypotension in three groups (sham-operated control, 2-3 hours postischemia, and 24 hours postischemia) of anesthetized newborn pigs equipped with closed cranial windows. Cerebral ischemia may eliminate the prostanoid vasodilator system from the cerebral circulation. Norepinephrine (10(-4) M) decreased pial arteriolar diameters similarly in all three groups (27%, 28%, and 21%, respectively), but only the sham-operated group exhibited pial arteriolar dilation in response to hypotension (28% at 33 mm Hg). Two-three and 24 hours after cerebral ischemia, hypotension decreased pial arteriolar diameters (21% and 17%, respectively). In sham-operated piglets, norepinephrine and hypotension increased cortical periarachnoid cerebrospinal fluid prostanoid concentrations. However, neither norepinephrine nor hypotension altered cerebral prostanoid production 2-3 or 24 hours after cerebral ischemia. Therefore, we conclude that after cerebral ischemia, autoregulatory pial arteriolar dilation in response to hypotension is absent, while vasoconstriction in response to norepinephrine is intact." @default.
- W2022033708 created "2016-06-24" @default.
- W2022033708 creator A5010883315 @default.
- W2022033708 creator A5018691607 @default.
- W2022033708 creator A5040836134 @default.
- W2022033708 creator A5053964764 @default.
- W2022033708 creator A5089052390 @default.
- W2022033708 date "1989-04-01" @default.
- W2022033708 modified "2023-09-26" @default.
- W2022033708 title "Postischemic cerebral microvascular responses to norepinephrine and hypotension in newborn pigs." @default.
- W2022033708 cites W1982386154 @default.
- W2022033708 cites W2023317778 @default.
- W2022033708 cites W2025832147 @default.
- W2022033708 cites W2028533213 @default.
- W2022033708 cites W2033661316 @default.
- W2022033708 cites W2033996133 @default.
- W2022033708 cites W2041073073 @default.
- W2022033708 cites W2067537931 @default.
- W2022033708 cites W2086755840 @default.
- W2022033708 cites W2156830520 @default.
- W2022033708 cites W2165191737 @default.
- W2022033708 cites W2166835169 @default.
- W2022033708 doi "https://doi.org/10.1161/01.str.20.4.541" @default.
- W2022033708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2929031" @default.
- W2022033708 hasPublicationYear "1989" @default.
- W2022033708 type Work @default.
- W2022033708 sameAs 2022033708 @default.
- W2022033708 citedByCount "45" @default.
- W2022033708 countsByYear W20220337082012 @default.
- W2022033708 countsByYear W20220337082013 @default.
- W2022033708 countsByYear W20220337082014 @default.
- W2022033708 countsByYear W20220337082018 @default.
- W2022033708 countsByYear W20220337082019 @default.
- W2022033708 countsByYear W20220337082020 @default.
- W2022033708 countsByYear W20220337082021 @default.
- W2022033708 crossrefType "journal-article" @default.
- W2022033708 hasAuthorship W2022033708A5010883315 @default.
- W2022033708 hasAuthorship W2022033708A5018691607 @default.
- W2022033708 hasAuthorship W2022033708A5040836134 @default.
- W2022033708 hasAuthorship W2022033708A5053964764 @default.
- W2022033708 hasAuthorship W2022033708A5089052390 @default.
- W2022033708 hasBestOaLocation W20220337081 @default.
- W2022033708 hasConcept C119671327 @default.
- W2022033708 hasConcept C120770815 @default.
- W2022033708 hasConcept C126322002 @default.
- W2022033708 hasConcept C157767197 @default.
- W2022033708 hasConcept C2778266237 @default.
- W2022033708 hasConcept C2778514916 @default.
- W2022033708 hasConcept C2779961880 @default.
- W2022033708 hasConcept C2780664492 @default.
- W2022033708 hasConcept C42219234 @default.
- W2022033708 hasConcept C513476851 @default.
- W2022033708 hasConcept C541997718 @default.
- W2022033708 hasConcept C71924100 @default.
- W2022033708 hasConceptScore W2022033708C119671327 @default.
- W2022033708 hasConceptScore W2022033708C120770815 @default.
- W2022033708 hasConceptScore W2022033708C126322002 @default.
- W2022033708 hasConceptScore W2022033708C157767197 @default.
- W2022033708 hasConceptScore W2022033708C2778266237 @default.
- W2022033708 hasConceptScore W2022033708C2778514916 @default.
- W2022033708 hasConceptScore W2022033708C2779961880 @default.
- W2022033708 hasConceptScore W2022033708C2780664492 @default.
- W2022033708 hasConceptScore W2022033708C42219234 @default.
- W2022033708 hasConceptScore W2022033708C513476851 @default.
- W2022033708 hasConceptScore W2022033708C541997718 @default.
- W2022033708 hasConceptScore W2022033708C71924100 @default.
- W2022033708 hasIssue "4" @default.
- W2022033708 hasLocation W20220337081 @default.
- W2022033708 hasLocation W20220337082 @default.
- W2022033708 hasOpenAccess W2022033708 @default.
- W2022033708 hasPrimaryLocation W20220337081 @default.
- W2022033708 hasRelatedWork W133587004 @default.
- W2022033708 hasRelatedWork W2019738578 @default.
- W2022033708 hasRelatedWork W2022033708 @default.
- W2022033708 hasRelatedWork W2036694802 @default.
- W2022033708 hasRelatedWork W204400932 @default.
- W2022033708 hasRelatedWork W2076674910 @default.
- W2022033708 hasRelatedWork W2118784284 @default.
- W2022033708 hasRelatedWork W2472000854 @default.
- W2022033708 hasRelatedWork W4240949467 @default.
- W2022033708 hasRelatedWork W4244497212 @default.
- W2022033708 hasVolume "20" @default.
- W2022033708 isParatext "false" @default.
- W2022033708 isRetracted "false" @default.
- W2022033708 magId "2022033708" @default.
- W2022033708 workType "article" @default.