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• W2022035369 abstract "In this study we examined the Golgi apparatus of avian notochord transplants excised from 2-day-old (E2) chick embryos and grafted isochronically into a chick host either in a medial-ventral position, next to the host notochord, or in a superficial position under the ectoderm laterally or dorsally to the neural tube. The operated embryos were examined from E2 to E8. The diameters, the cytoplasmic vacuolization and the immunostained Golgi apparatus were identical between the endogenous and ventrally grafted notochords, as well as between host-and superficially transplanted notochords when observed at E2. In contrast, from E4 to E8, the size of the notochords grafted dorsally or laterally to the neural tube was significantly smaller than the host, while the cytoplasmic vacuolization and the degree of fragmentation of the Golgi apparatus were significantly less than in the host notochords. These results show that environmental and position-specific factors influence the developmental program and the secretory activity of the notochordal cells. Nous avons analysé l'appareil de Golgi (AG) de notochordes prélevées à deux j d'incubation (E2) sur des embryons de poulet, puis transplantées dans un embryon du même stade, soit en position médioventrale, parallèle à la notochorde du receveur, soit en position sous-ectodermique, latéralement ou dorsalement par rapport au tube neural. Les embryons opérés ont été examinés de E2 à E8. Le diamètre de la notochorde, la vacuolisation cytoplasmique et la morphologie de l'AG sont similaires a) pour la notochorde endogène et les transplants ventraux, b) pour la notochorde de l'hôte et les transplants dorsaux à E2 uniquement. De E4 à E8, le diamètre des greffons dorsaux ou latéraux est inférieur à celui de la notochorde du receveur, tandis que la vacuolisation cytoplasmique et le degré de fragmentation de l'AG sont nettement réduits. Ces résultats montrent que l'environnement ainsi que des facteurs de position influencent le programme de développement et l'activité sécrétoire des cellules de la notochorde." @default.
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• W2022035369 date "1998-08-01" @default.
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• W2022035369 title "Environmental factors modulate the size and the secretory activity of the notochord. A study of the Golgi apparatus in avian embryos" @default.
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• W2022035369 doi "https://doi.org/10.1016/s0764-4469(98)80001-2" @default.
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