FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022038903> ?p ?o ?g. }

• W2022038903 endingPage "986" @default.
• W2022038903 startingPage "979" @default.
• W2022038903 abstract "It is common practice during one lung ventilation (OLV) to use 100% oxygen, although this may cause hyperoxia- and oxidative stress-related lung injury. We hypothesized that lower oxygen (FiO(2) ) during OLV will result in less inflammatory and oxidative lung injury and improved lung function.Twenty pigs (8.88 ± 0.84 kg; 38 ± 4.6 days) were assigned to either the hyperoxia group (n = 10; FiO(2) = 100%) or the normoxia group (n = 10; FiO(2) < 50%). Both groups were subjected to 3 hr of OLV. Blood samples were tested for pro-inflammatory cytokines and lung tissue was tested for these cytokines and oxidative biomarkers.There were no differences between groups for partial pressure of CO(2) , tidal volume, end-tidal CO(2) , plasma cytokines, or respiratory compliance. Total respiratory resistance was greater in the hyperoxia group (P = 0.02). There were higher levels of TNF-α, IL-1β, and IL-6 in the lung homogenates of the hyperoxia group than in the normoxia group (P ≤ 0.01, 0.001, and 0.001, respectively). Myeloperoxidase and protein carbonyls (PC) were higher (P = 0.03 and P = 0.01, respectively) and superoxide dismutase (SOD) was lower in the lung homogenates of the hyperoxia group (P ≤ 0.001).Higher myeloperoxidase, PC, and cytokine levels, and lower SOD availability indicate a greater degree of injury in the lungs of the hyperoxia animals, possibly from using 100% oxygen. In this translational study using a pig model, FiO(2) ≤ 50% during OLV reduced hyperoxic injury and improved function in the lungs." @default.
• W2022038903 created "2016-06-24" @default.
• W2022038903 creator A5033175999 @default.
• W2022038903 creator A5037250493 @default.
• W2022038903 creator A5046695124 @default.
• W2022038903 creator A5049561563 @default.
• W2022038903 creator A5052918964 @default.
• W2022038903 creator A5071164761 @default.
• W2022038903 creator A5078321152 @default.
• W2022038903 date "2012-03-19" @default.
• W2022038903 modified "2023-10-09" @default.
• W2022038903 title "Hyperoxia during one lung ventilation: Inflammatory and oxidative responses" @default.
• W2022038903 cites W1810046561 @default.
• W2022038903 cites W1965693998 @default.
• W2022038903 cites W1970232637 @default.
• W2022038903 cites W1970778161 @default.
• W2022038903 cites W1982388830 @default.
• W2022038903 cites W1984993425 @default.
• W2022038903 cites W2012627045 @default.
• W2022038903 cites W2013724392 @default.
• W2022038903 cites W2021470748 @default.
• W2022038903 cites W2027434093 @default.
• W2022038903 cites W2032865299 @default.
• W2022038903 cites W2036032946 @default.
• W2022038903 cites W2044877141 @default.
• W2022038903 cites W2048937730 @default.
• W2022038903 cites W2055156374 @default.
• W2022038903 cites W2057725352 @default.
• W2022038903 cites W2058471525 @default.
• W2022038903 cites W2060517316 @default.
• W2022038903 cites W2062472058 @default.
• W2022038903 cites W2064095692 @default.
• W2022038903 cites W2066700215 @default.
• W2022038903 cites W2074152729 @default.
• W2022038903 cites W2079860656 @default.
• W2022038903 cites W2086690247 @default.
• W2022038903 cites W2089951589 @default.
• W2022038903 cites W2098562755 @default.
• W2022038903 cites W2109958428 @default.
• W2022038903 cites W2110144260 @default.
• W2022038903 cites W2121686888 @default.
• W2022038903 cites W2128862148 @default.
• W2022038903 cites W2136040027 @default.
• W2022038903 cites W2148000616 @default.
• W2022038903 cites W2150104010 @default.
• W2022038903 cites W2410144603 @default.
• W2022038903 doi "https://doi.org/10.1002/ppul.22517" @default.
• W2022038903 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3888791" @default.
• W2022038903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22431368" @default.
• W2022038903 hasPublicationYear "2012" @default.
• W2022038903 type Work @default.
• W2022038903 sameAs 2022038903 @default.
• W2022038903 citedByCount "34" @default.
• W2022038903 countsByYear W20220389032013 @default.
• W2022038903 countsByYear W20220389032014 @default.
• W2022038903 countsByYear W20220389032015 @default.
• W2022038903 countsByYear W20220389032016 @default.
• W2022038903 countsByYear W20220389032017 @default.
• W2022038903 countsByYear W20220389032018 @default.
• W2022038903 countsByYear W20220389032019 @default.
• W2022038903 countsByYear W20220389032020 @default.
• W2022038903 countsByYear W20220389032021 @default.
• W2022038903 countsByYear W20220389032022 @default.
• W2022038903 crossrefType "journal-article" @default.
• W2022038903 hasAuthorship W2022038903A5033175999 @default.
• W2022038903 hasAuthorship W2022038903A5037250493 @default.
• W2022038903 hasAuthorship W2022038903A5046695124 @default.
• W2022038903 hasAuthorship W2022038903A5049561563 @default.
• W2022038903 hasAuthorship W2022038903A5052918964 @default.
• W2022038903 hasAuthorship W2022038903A5071164761 @default.
• W2022038903 hasAuthorship W2022038903A5078321152 @default.
• W2022038903 hasBestOaLocation W20220389032 @default.
• W2022038903 hasConcept C126322002 @default.
• W2022038903 hasConcept C127413603 @default.
• W2022038903 hasConcept C136936797 @default.
• W2022038903 hasConcept C200457457 @default.
• W2022038903 hasConcept C203565725 @default.
• W2022038903 hasConcept C2775838275 @default.
• W2022038903 hasConcept C2776151105 @default.
• W2022038903 hasConcept C2776914184 @default.
• W2022038903 hasConcept C2777257755 @default.
• W2022038903 hasConcept C2777714996 @default.
• W2022038903 hasConcept C2780672939 @default.
• W2022038903 hasConcept C42219234 @default.
• W2022038903 hasConcept C534529494 @default.
• W2022038903 hasConcept C71924100 @default.
• W2022038903 hasConcept C78519656 @default.
• W2022038903 hasConceptScore W2022038903C126322002 @default.
• W2022038903 hasConceptScore W2022038903C127413603 @default.
• W2022038903 hasConceptScore W2022038903C136936797 @default.
• W2022038903 hasConceptScore W2022038903C200457457 @default.
• W2022038903 hasConceptScore W2022038903C203565725 @default.
• W2022038903 hasConceptScore W2022038903C2775838275 @default.
• W2022038903 hasConceptScore W2022038903C2776151105 @default.
• W2022038903 hasConceptScore W2022038903C2776914184 @default.
• W2022038903 hasConceptScore W2022038903C2777257755 @default.
• W2022038903 hasConceptScore W2022038903C2777714996 @default.
• W2022038903 hasConceptScore W2022038903C2780672939 @default.

• next