Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022040401> ?p ?o ?g. }
- W2022040401 endingPage "1131" @default.
- W2022040401 startingPage "1131" @default.
- W2022040401 abstract "Objective To examine default mode and salience network functional connectivity as a function of APOE ε4 status in a group of cognitively normal age-, sex-, and education-matched older adults. Design Case-control study. Subjects Fifty-six cognitively normal APOE ε4 carriers and 56 age-, sex- and education-matched cognitively normal APOE ε4 noncarriers. Main Outcome Measure Alterations in in-phase default mode and salience network connectivity in APOE ε4 carriers compared with APOE ε4 noncarriers ranging from 63 to 91 years of age. Results A posterior cingulate seed revealed decreased in-phase connectivity in regions of the posterior default mode network that included the left inferior parietal lobe, left middle temporal gyrus, and bilateral anterior temporal lobes in the ε4 carriers relative to APOE ε4 noncarriers. An anterior cingulate seed showed greater in-phase connectivity in the salience network including the cingulate gyrus, medial prefrontal cortex, bilateral insular cortex, striatum, and thalamus in APOE ε4 carriers vs noncarriers. There were no groupwise differences in brain anatomy. Conclusions The observation of functional alterations in default mode and salience network connectivity in the absence of structural changes between APOE ε4 carriers and noncarriers suggests that alterations in connectivity may have the potential to serve as an early biomarker." @default.
- W2022040401 created "2016-06-24" @default.
- W2022040401 creator A5005099850 @default.
- W2022040401 creator A5010832408 @default.
- W2022040401 creator A5017098899 @default.
- W2022040401 creator A5026250910 @default.
- W2022040401 creator A5032297807 @default.
- W2022040401 creator A5043921358 @default.
- W2022040401 creator A5045246745 @default.
- W2022040401 creator A5059027860 @default.
- W2022040401 creator A5063489595 @default.
- W2022040401 creator A5068373508 @default.
- W2022040401 date "2011-09-01" @default.
- W2022040401 modified "2023-09-25" @default.
- W2022040401 title "Effect of <i>APOE</i> ε4 Status on Intrinsic Network Connectivity in Cognitively Normal Elderly Subjects" @default.
- W2022040401 cites W1484611135 @default.
- W2022040401 cites W1760829075 @default.
- W2022040401 cites W1974594322 @default.
- W2022040401 cites W1985327120 @default.
- W2022040401 cites W1991952617 @default.
- W2022040401 cites W1993541461 @default.
- W2022040401 cites W1994184572 @default.
- W2022040401 cites W1997301424 @default.
- W2022040401 cites W1999631936 @default.
- W2022040401 cites W2002586787 @default.
- W2022040401 cites W2014897304 @default.
- W2022040401 cites W2017079501 @default.
- W2022040401 cites W2020780341 @default.
- W2022040401 cites W2025577666 @default.
- W2022040401 cites W2040178194 @default.
- W2022040401 cites W2041325253 @default.
- W2022040401 cites W2041892844 @default.
- W2022040401 cites W2055345898 @default.
- W2022040401 cites W2057550180 @default.
- W2022040401 cites W2060629467 @default.
- W2022040401 cites W2062843923 @default.
- W2022040401 cites W2072220916 @default.
- W2022040401 cites W2074829442 @default.
- W2022040401 cites W2078524519 @default.
- W2022040401 cites W2079450984 @default.
- W2022040401 cites W2081718320 @default.
- W2022040401 cites W2101334128 @default.
- W2022040401 cites W2102641992 @default.
- W2022040401 cites W2103717170 @default.
- W2022040401 cites W2116658855 @default.
- W2022040401 cites W2119848633 @default.
- W2022040401 cites W2126650951 @default.
- W2022040401 cites W2132065430 @default.
- W2022040401 cites W2134858198 @default.
- W2022040401 cites W2135475851 @default.
- W2022040401 cites W2136573752 @default.
- W2022040401 cites W2143285014 @default.
- W2022040401 cites W2149240084 @default.
- W2022040401 cites W2155369114 @default.
- W2022040401 cites W2158592797 @default.
- W2022040401 cites W2162010696 @default.
- W2022040401 cites W2171346860 @default.
- W2022040401 cites W4206679801 @default.
- W2022040401 cites W4230078834 @default.
- W2022040401 cites W4230920194 @default.
- W2022040401 cites W4256188663 @default.
- W2022040401 doi "https://doi.org/10.1001/archneurol.2011.108" @default.
- W2022040401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3392960" @default.
- W2022040401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21555604" @default.
- W2022040401 hasPublicationYear "2011" @default.
- W2022040401 type Work @default.
- W2022040401 sameAs 2022040401 @default.
- W2022040401 citedByCount "193" @default.
- W2022040401 countsByYear W20220404012012 @default.
- W2022040401 countsByYear W20220404012013 @default.
- W2022040401 countsByYear W20220404012014 @default.
- W2022040401 countsByYear W20220404012015 @default.
- W2022040401 countsByYear W20220404012016 @default.
- W2022040401 countsByYear W20220404012017 @default.
- W2022040401 countsByYear W20220404012018 @default.
- W2022040401 countsByYear W20220404012019 @default.
- W2022040401 countsByYear W20220404012020 @default.
- W2022040401 countsByYear W20220404012021 @default.
- W2022040401 countsByYear W20220404012022 @default.
- W2022040401 countsByYear W20220404012023 @default.
- W2022040401 crossrefType "journal-article" @default.
- W2022040401 hasAuthorship W2022040401A5005099850 @default.
- W2022040401 hasAuthorship W2022040401A5010832408 @default.
- W2022040401 hasAuthorship W2022040401A5017098899 @default.
- W2022040401 hasAuthorship W2022040401A5026250910 @default.
- W2022040401 hasAuthorship W2022040401A5032297807 @default.
- W2022040401 hasAuthorship W2022040401A5043921358 @default.
- W2022040401 hasAuthorship W2022040401A5045246745 @default.
- W2022040401 hasAuthorship W2022040401A5059027860 @default.
- W2022040401 hasAuthorship W2022040401A5063489595 @default.
- W2022040401 hasAuthorship W2022040401A5068373508 @default.
- W2022040401 hasBestOaLocation W20220404011 @default.
- W2022040401 hasConcept C108154423 @default.
- W2022040401 hasConcept C126322002 @default.
- W2022040401 hasConcept C141516989 @default.
- W2022040401 hasConcept C15744967 @default.
- W2022040401 hasConcept C169760540 @default.
- W2022040401 hasConcept C169900460 @default.