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• W2022041364 abstract "Interleukin-1 alpha (IL-1 alpha) acts in vitro to enhance the gene expression of colony-stimulating factor-1 (CSF-1) of dental follicle cells. Because the dental follicle is required for tooth eruption and because CSF-1 appears to be a key molecule in initiating eruption, it was the aim of this study to determine if IL-1 alpha could enhance the expression of the CSF-1 gene in the dental follicle in vivo. To determine this, rats were injected with IL-1 alpha at different ages postnatally and the total RNA was isolated from the dental follicles of the first mandibular molars. Reverse transcription-polymerase chain reaction showed that IL-1 alpha enhanced the expression of CSF-1 in the follicle. Thus, IL-1 alpha may play a part in the cascade of molecular signals that initiate eruption by its effect upon the CSF-1 gene." @default.
• W2022041364 created "2016-06-24" @default.
• W2022041364 creator A5084628799 @default.
• W2022041364 date "1998-04-01" @default.
• W2022041364 modified "2023-10-16" @default.
• W2022041364 title "In vivo effect of interleukin-1α on colony-stimulating factor-1 gene expression in the dental follicle of the rat molar" @default.
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• W2022041364 doi "https://doi.org/10.1016/s0003-9969(97)00102-7" @default.
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