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• W2022042640 abstract "The in vitro and in vivo genetic toxicity tests currently in use for chemical screening and for regulatory approval of chemical substances evolved from a larger series of tests that were found useful for identifying germ cell mutagens and clastogens, and carcinogens. This article provides a brief history of genetic toxicity testing, the philosophy behind the selection of the tests currently in use and their recommended combinations, brief descriptions of the various in vitro and in vivo tests for identifying presumptive carcinogens and germ cell mutagens, and recent and anticipated changes in the test systems used. Also presented are general procedures and precautions that need to be followed for performing the tests and submitting the tests to regulatory authorities." @default.
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• W2022042640 date "1987-10-01" @default.
• W2022042640 modified "2023-10-16" @default.
• W2022042640 title "Guide for performing the mouse lymphoma assay for mammalian cell mutagenicity" @default.
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• W2022042640 doi "https://doi.org/10.1016/0165-1218(87)90020-6" @default.
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