Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022042901> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2022042901 endingPage "362" @default.
- W2022042901 startingPage "357" @default.
- W2022042901 abstract "Ribosomal protein S6 kinase (S6K) is a key regulator of cell size and growth. It is regulated via phosphoinositide 3‐kinases (PI3K) and the mammalian target of rapamycin (mTOR) signaling pathways. We demonstrate for the first time that CoA synthase associates specifically with S6K1. The association was observed between native and transiently overexpressed proteins in vivo, as well as by BIAcore analysis in vitro. The sites of interaction were mapped to the C‐terminal regions of both CoA synthase and S6K1. In vitro studies indicated that the interaction does not affect their enzymatic activities and that CoA synthase is not a substrate for S6 kinase. This study uncovers a potential link between mTor/S6K signaling pathway and energy metabolism through CoA and its thioester derivatives, but its physiological relevance should be further elucidated." @default.
- W2022042901 created "2016-06-24" @default.
- W2022042901 creator A5013546354 @default.
- W2022042901 creator A5033772913 @default.
- W2022042901 creator A5040592899 @default.
- W2022042901 creator A5053580679 @default.
- W2022042901 creator A5056656950 @default.
- W2022042901 creator A5072057688 @default.
- W2022042901 date "2004-11-16" @default.
- W2022042901 modified "2023-10-17" @default.
- W2022042901 title "Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism" @default.
- W2022042901 cites W1493922188 @default.
- W2022042901 cites W1963723155 @default.
- W2022042901 cites W1972317299 @default.
- W2022042901 cites W1982558191 @default.
- W2022042901 cites W2018274938 @default.
- W2022042901 cites W2050988292 @default.
- W2022042901 cites W2056137479 @default.
- W2022042901 cites W2067765926 @default.
- W2022042901 cites W2071618706 @default.
- W2022042901 cites W2087812126 @default.
- W2022042901 cites W2090632954 @default.
- W2022042901 cites W2094853437 @default.
- W2022042901 cites W2096131954 @default.
- W2022042901 cites W2099389441 @default.
- W2022042901 cites W2099442582 @default.
- W2022042901 cites W2115248647 @default.
- W2022042901 cites W2125937054 @default.
- W2022042901 cites W2334057992 @default.
- W2022042901 doi "https://doi.org/10.1016/j.febslet.2004.10.091" @default.
- W2022042901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15589845" @default.
- W2022042901 hasPublicationYear "2004" @default.
- W2022042901 type Work @default.
- W2022042901 sameAs 2022042901 @default.
- W2022042901 citedByCount "32" @default.
- W2022042901 countsByYear W20220429012012 @default.
- W2022042901 countsByYear W20220429012013 @default.
- W2022042901 countsByYear W20220429012014 @default.
- W2022042901 countsByYear W20220429012015 @default.
- W2022042901 countsByYear W20220429012016 @default.
- W2022042901 countsByYear W20220429012017 @default.
- W2022042901 countsByYear W20220429012018 @default.
- W2022042901 countsByYear W20220429012019 @default.
- W2022042901 countsByYear W20220429012020 @default.
- W2022042901 countsByYear W20220429012021 @default.
- W2022042901 countsByYear W20220429012023 @default.
- W2022042901 crossrefType "journal-article" @default.
- W2022042901 hasAuthorship W2022042901A5013546354 @default.
- W2022042901 hasAuthorship W2022042901A5033772913 @default.
- W2022042901 hasAuthorship W2022042901A5040592899 @default.
- W2022042901 hasAuthorship W2022042901A5053580679 @default.
- W2022042901 hasAuthorship W2022042901A5056656950 @default.
- W2022042901 hasAuthorship W2022042901A5072057688 @default.
- W2022042901 hasBestOaLocation W20220429011 @default.
- W2022042901 hasConcept C104202773 @default.
- W2022042901 hasConcept C112243037 @default.
- W2022042901 hasConcept C11960822 @default.
- W2022042901 hasConcept C173990801 @default.
- W2022042901 hasConcept C181199279 @default.
- W2022042901 hasConcept C184235292 @default.
- W2022042901 hasConcept C185592680 @default.
- W2022042901 hasConcept C55493867 @default.
- W2022042901 hasConcept C62478195 @default.
- W2022042901 hasConcept C86554907 @default.
- W2022042901 hasConcept C86803240 @default.
- W2022042901 hasConcept C95444343 @default.
- W2022042901 hasConceptScore W2022042901C104202773 @default.
- W2022042901 hasConceptScore W2022042901C112243037 @default.
- W2022042901 hasConceptScore W2022042901C11960822 @default.
- W2022042901 hasConceptScore W2022042901C173990801 @default.
- W2022042901 hasConceptScore W2022042901C181199279 @default.
- W2022042901 hasConceptScore W2022042901C184235292 @default.
- W2022042901 hasConceptScore W2022042901C185592680 @default.
- W2022042901 hasConceptScore W2022042901C55493867 @default.
- W2022042901 hasConceptScore W2022042901C62478195 @default.
- W2022042901 hasConceptScore W2022042901C86554907 @default.
- W2022042901 hasConceptScore W2022042901C86803240 @default.
- W2022042901 hasConceptScore W2022042901C95444343 @default.
- W2022042901 hasIssue "3" @default.
- W2022042901 hasLocation W20220429011 @default.
- W2022042901 hasLocation W20220429012 @default.
- W2022042901 hasOpenAccess W2022042901 @default.
- W2022042901 hasPrimaryLocation W20220429011 @default.
- W2022042901 hasRelatedWork W104690111 @default.
- W2022042901 hasRelatedWork W2000522159 @default.
- W2022042901 hasRelatedWork W2006559495 @default.
- W2022042901 hasRelatedWork W2012886371 @default.
- W2022042901 hasRelatedWork W2138871725 @default.
- W2022042901 hasRelatedWork W2144059623 @default.
- W2022042901 hasRelatedWork W2265863784 @default.
- W2022042901 hasRelatedWork W4212829917 @default.
- W2022042901 hasRelatedWork W4248518057 @default.
- W2022042901 hasRelatedWork W4309779541 @default.
- W2022042901 hasVolume "578" @default.
- W2022042901 isParatext "false" @default.
- W2022042901 isRetracted "false" @default.
- W2022042901 magId "2022042901" @default.
- W2022042901 workType "article" @default.