FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022045091> ?p ?o ?g. }

• W2022045091 endingPage "467" @default.
• W2022045091 startingPage "461" @default.
• W2022045091 abstract "Approximately half of cancer patients scheduled for major surgery are anemic. Also, a significant number of patients will present to the operating room with low platelet counts and coagulopathic disorders. Unfortunately, administration of red blood cells, platelets concentrates and fresh-frozen plasma is associated with unwanted adverse effects including fever, hemolytic reactions and transfusion-related immunomodulation (TRIM). TRIM is a multifactorial immunologic phenomenon in the recipient mediated by donor leukocytes, microparticles such as ectosomes, and growth factors. As some of these molecules are secreted in a time-dependent manner, blood storage time may play an important in TRIM, although the evidence is limited. Perioperative administration of red blood cells and associated TRIM has also been associated with increased recurrence of certain solid tumors, such as colorectal, lung, and hepatobiliary tumors. In this continuing education article, we review the available evidence on how perioperative blood product transfusions can affect oncological outcomes, such as cancer recurrence. Aproximadamente 50% de los pacientes oncológicos que se presentan para cirugía mayor están anémicos. Una cantidad importante de estos pacientes también están plaquetopénicos y/o con trastornos en sus vías de coagulación. Si bien la transfusiones de productos derivados de la sangre se usan para corregir defectos perioperatorios hematológicos, estos productos han sido implicados como inductores de inmunosupresión. Esta ultima es de origen multifactorial ya que factores de crecimiento, leucocitos y macropartículas presentes en las bolsas de productos sanguíneos han sido implicado como algunos de los mecanismos de inmunosupresión. Es importante destacar que a la inmunosupresión asociada a las transfusiones perioperatorias de sangre se la ha relacionado como uno de los mecanismos por los cuales existe una tasa de recurrencia de cáncer colorectal, pulmonar y hepatobiliar. En este manuscrito de formación continuada discutirá la evidencia existente acerca de la relación entre anemia, transfusión de productos de la sangre y recurrencia de cáncer." @default.
• W2022045091 created "2016-06-24" @default.
• W2022045091 creator A5025645999 @default.
• W2022045091 creator A5084205539 @default.
• W2022045091 date "2015-10-01" @default.
• W2022045091 modified "2023-10-03" @default.
• W2022045091 title "Transfusions of blood products and cancer outcomes" @default.
• W2022045091 cites W1490221167 @default.
• W2022045091 cites W1506209090 @default.
• W2022045091 cites W1526053221 @default.
• W2022045091 cites W1583843737 @default.
• W2022045091 cites W1670312086 @default.
• W2022045091 cites W1916911084 @default.
• W2022045091 cites W1964671813 @default.
• W2022045091 cites W1985678350 @default.
• W2022045091 cites W1988351795 @default.
• W2022045091 cites W1995143174 @default.
• W2022045091 cites W1995293361 @default.
• W2022045091 cites W1997306347 @default.
• W2022045091 cites W2002039295 @default.
• W2022045091 cites W2004542691 @default.
• W2022045091 cites W2008668845 @default.
• W2022045091 cites W2012119020 @default.
• W2022045091 cites W2030466615 @default.
• W2022045091 cites W2030809542 @default.
• W2022045091 cites W2036015516 @default.
• W2022045091 cites W2039531690 @default.
• W2022045091 cites W2050985964 @default.
• W2022045091 cites W2057237518 @default.
• W2022045091 cites W2066357594 @default.
• W2022045091 cites W2071975253 @default.
• W2022045091 cites W2072227408 @default.
• W2022045091 cites W2076458451 @default.
• W2022045091 cites W2094961596 @default.
• W2022045091 cites W2110048044 @default.
• W2022045091 cites W2114915301 @default.
• W2022045091 cites W2122808607 @default.
• W2022045091 cites W2124796556 @default.
• W2022045091 cites W2125198595 @default.
• W2022045091 cites W2126868459 @default.
• W2022045091 cites W2133623557 @default.
• W2022045091 cites W2138604998 @default.
• W2022045091 cites W2144351151 @default.
• W2022045091 cites W2152207843 @default.
• W2022045091 cites W2152834195 @default.
• W2022045091 cites W2158441687 @default.
• W2022045091 cites W2990769636 @default.
• W2022045091 cites W4249811720 @default.
• W2022045091 doi "https://doi.org/10.1016/j.redar.2015.02.013" @default.
• W2022045091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25896733" @default.
• W2022045091 hasPublicationYear "2015" @default.
• W2022045091 type Work @default.
• W2022045091 sameAs 2022045091 @default.
• W2022045091 citedByCount "19" @default.
• W2022045091 countsByYear W20220450912016 @default.
• W2022045091 countsByYear W20220450912017 @default.
• W2022045091 countsByYear W20220450912018 @default.
• W2022045091 countsByYear W20220450912019 @default.
• W2022045091 countsByYear W20220450912020 @default.
• W2022045091 countsByYear W20220450912021 @default.
• W2022045091 countsByYear W20220450912022 @default.
• W2022045091 crossrefType "journal-article" @default.
• W2022045091 hasAuthorship W2022045091A5025645999 @default.
• W2022045091 hasAuthorship W2022045091A5084205539 @default.
• W2022045091 hasConcept C121608353 @default.
• W2022045091 hasConcept C126322002 @default.
• W2022045091 hasConcept C141071460 @default.
• W2022045091 hasConcept C197934379 @default.
• W2022045091 hasConcept C203014093 @default.
• W2022045091 hasConcept C2776738589 @default.
• W2022045091 hasConcept C2777396833 @default.
• W2022045091 hasConcept C31174226 @default.
• W2022045091 hasConcept C66112548 @default.
• W2022045091 hasConcept C71924100 @default.
• W2022045091 hasConcept C89560881 @default.
• W2022045091 hasConcept C90924648 @default.
• W2022045091 hasConceptScore W2022045091C121608353 @default.
• W2022045091 hasConceptScore W2022045091C126322002 @default.
• W2022045091 hasConceptScore W2022045091C141071460 @default.
• W2022045091 hasConceptScore W2022045091C197934379 @default.
• W2022045091 hasConceptScore W2022045091C203014093 @default.
• W2022045091 hasConceptScore W2022045091C2776738589 @default.
• W2022045091 hasConceptScore W2022045091C2777396833 @default.
• W2022045091 hasConceptScore W2022045091C31174226 @default.
• W2022045091 hasConceptScore W2022045091C66112548 @default.
• W2022045091 hasConceptScore W2022045091C71924100 @default.
• W2022045091 hasConceptScore W2022045091C89560881 @default.
• W2022045091 hasConceptScore W2022045091C90924648 @default.
• W2022045091 hasIssue "8" @default.
• W2022045091 hasLocation W20220450911 @default.
• W2022045091 hasLocation W20220450912 @default.
• W2022045091 hasOpenAccess W2022045091 @default.
• W2022045091 hasPrimaryLocation W20220450911 @default.
• W2022045091 hasRelatedWork W1994006788 @default.
• W2022045091 hasRelatedWork W2032504685 @default.
• W2022045091 hasRelatedWork W2111669357 @default.
• W2022045091 hasRelatedWork W2116363559 @default.
• W2022045091 hasRelatedWork W2348093099 @default.

• next