FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022047741> ?p ?o ?g. }

• W2022047741 endingPage "520" @default.
• W2022047741 startingPage "512" @default.
• W2022047741 abstract "Impaired cortical plasticity may be part of the core pathophysiology of schizophrenia (SZ). Long-term potentiation is a form of neuroplasticity that has been recently demonstrated in humans by showing that repetitive visual stimulation produces lasting enhancement of visual evoked potentials (VEP). Using this paradigm, we examined whether visual cortical plasticity is impaired in SZ.Electroencephalographic data were recorded from 19 SZ and 22 healthy control (HC) subjects during a visual long-term potentiation paradigm. Visual evoked potentials were elicited by standard visual stimuli (∼.83 Hz, 2-minute blocks) at baseline and at 2, 4, and 20 minutes following exposure to visual high-frequency stimulation (HFS) (∼8.8 Hz, 2 minutes) designed to induce VEP potentiation. To ensure attentiveness during VEP assessments, subjects responded with a button press to infrequent (10%) target stimuli. Visual evoked potentials were subjected to principal components analysis. Two negative-voltage components prominent over occipital-parietal electrode sites were evident at 92 msec (C1) and at 146 msec (N1b). Changes in C1 and N1b component scores from baseline to the post-HFS assessments were compared between groups.High-frequency stimulation produced sustained potentiation of visual C1 and N1b in HCs but not in SZs. The HCs and SZs had comparable HFS-driven electroencephalographic visual steady state responses. However, greater visual steady state responses to the HFS predicted greater N1b potentiation in HCs but not in SZs. Schizophrenia patients with greater N1b potentiation decreased their reaction times to target stimuli.Visual cortical plasticity is impaired in schizophrenia, consistent with hypothesized deficits in N-methyl-D-aspartate receptor function." @default.
• W2022047741 created "2016-06-24" @default.
• W2022047741 creator A5001798382 @default.
• W2022047741 creator A5020339164 @default.
• W2022047741 creator A5022941543 @default.
• W2022047741 creator A5045359695 @default.
• W2022047741 creator A5052366236 @default.
• W2022047741 creator A5053921657 @default.
• W2022047741 creator A5060218225 @default.
• W2022047741 creator A5071039477 @default.
• W2022047741 creator A5072749197 @default.
• W2022047741 date "2012-03-01" @default.
• W2022047741 modified "2023-09-24" @default.
• W2022047741 title "Impaired Visual Cortical Plasticity in Schizophrenia" @default.
• W2022047741 cites W1964857285 @default.
• W2022047741 cites W1966111889 @default.
• W2022047741 cites W1968584106 @default.
• W2022047741 cites W1972556520 @default.
• W2022047741 cites W1978675813 @default.
• W2022047741 cites W1979559749 @default.
• W2022047741 cites W1980073907 @default.
• W2022047741 cites W1982580579 @default.
• W2022047741 cites W1984092261 @default.
• W2022047741 cites W1989902442 @default.
• W2022047741 cites W1991661467 @default.
• W2022047741 cites W1992156655 @default.
• W2022047741 cites W1993608276 @default.
• W2022047741 cites W1994681591 @default.
• W2022047741 cites W1994855515 @default.
• W2022047741 cites W1997695932 @default.
• W2022047741 cites W1998074810 @default.
• W2022047741 cites W1998679999 @default.
• W2022047741 cites W2000433175 @default.
• W2022047741 cites W2017145381 @default.
• W2022047741 cites W2020140782 @default.
• W2022047741 cites W2032210947 @default.
• W2022047741 cites W2037420423 @default.
• W2022047741 cites W2040328720 @default.
• W2022047741 cites W2040709031 @default.
• W2022047741 cites W2046105255 @default.
• W2022047741 cites W2048148469 @default.
• W2022047741 cites W2050521769 @default.
• W2022047741 cites W2055417053 @default.
• W2022047741 cites W2056678372 @default.
• W2022047741 cites W2071090720 @default.
• W2022047741 cites W2071638142 @default.
• W2022047741 cites W2085846947 @default.
• W2022047741 cites W2092691745 @default.
• W2022047741 cites W2098708988 @default.
• W2022047741 cites W2099085951 @default.
• W2022047741 cites W2102454701 @default.
• W2022047741 cites W2102748918 @default.
• W2022047741 cites W2108889104 @default.
• W2022047741 cites W2112468165 @default.
• W2022047741 cites W2114512489 @default.
• W2022047741 cites W2115821201 @default.
• W2022047741 cites W2118227489 @default.
• W2022047741 cites W2134927362 @default.
• W2022047741 cites W2135837826 @default.
• W2022047741 cites W2136273577 @default.
• W2022047741 cites W2136592274 @default.
• W2022047741 cites W2140606211 @default.
• W2022047741 cites W2144641861 @default.
• W2022047741 cites W2145677204 @default.
• W2022047741 cites W2148849468 @default.
• W2022047741 cites W2149954813 @default.
• W2022047741 cites W2152401380 @default.
• W2022047741 cites W2152811887 @default.
• W2022047741 cites W2163563093 @default.
• W2022047741 cites W2172137638 @default.
• W2022047741 cites W2397257824 @default.
• W2022047741 cites W2417819953 @default.
• W2022047741 cites W39535334 @default.
• W2022047741 doi "https://doi.org/10.1016/j.biopsych.2012.01.013" @default.
• W2022047741 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3292767" @default.
• W2022047741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22364738" @default.
• W2022047741 hasPublicationYear "2012" @default.
• W2022047741 type Work @default.
• W2022047741 sameAs 2022047741 @default.
• W2022047741 citedByCount "113" @default.
• W2022047741 countsByYear W20220477412012 @default.
• W2022047741 countsByYear W20220477412013 @default.
• W2022047741 countsByYear W20220477412014 @default.
• W2022047741 countsByYear W20220477412015 @default.
• W2022047741 countsByYear W20220477412016 @default.
• W2022047741 countsByYear W20220477412017 @default.
• W2022047741 countsByYear W20220477412018 @default.
• W2022047741 countsByYear W20220477412019 @default.
• W2022047741 countsByYear W20220477412020 @default.
• W2022047741 countsByYear W20220477412021 @default.
• W2022047741 countsByYear W20220477412022 @default.
• W2022047741 countsByYear W20220477412023 @default.
• W2022047741 crossrefType "journal-article" @default.
• W2022047741 hasAuthorship W2022047741A5001798382 @default.
• W2022047741 hasAuthorship W2022047741A5020339164 @default.
• W2022047741 hasAuthorship W2022047741A5022941543 @default.
• W2022047741 hasAuthorship W2022047741A5045359695 @default.
• W2022047741 hasAuthorship W2022047741A5052366236 @default.

• next