Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022054435> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2022054435 endingPage "14" @default.
- W2022054435 startingPage "12" @default.
- W2022054435 abstract "The selective α2-adrenoceptor antagonist, RX781094, evoked a dose-related pressor response in the pithed rat preparation when administered in bolus doses by the intravenous route. This response was enhanced following depletion of endogenous amines by reserpine, and inhibited by the selective α1-adrenoceptor antagonist, prazosin. Two other selective α2-adrenoceptor antagonists, Wy 26703 and Wy 26392, had no marked effect on the blood pressure of this preparation. Pretreatment of the preparation with Wy 26703 had no significant effect on the pressor response evoked by RX781094. It is concluded that RX781094 is an α1-adrenoceptor agonist at similar doses to those at which it exhibits α2-adrenoceptor antagonist properties. The agonist activity exhibited by RX781094 is not a general property of all α2-adrenoceptor antagonists and should be considered when this compound is employed as an α2-adrenoceptor antagonist." @default.
- W2022054435 created "2016-06-24" @default.
- W2022054435 creator A5056346637 @default.
- W2022054435 creator A5072251831 @default.
- W2022054435 date "1983-05-01" @default.
- W2022054435 modified "2023-09-26" @default.
- W2022054435 title "α1-Adrenoceptor agonist activity of α2-adrenoceptor antagonists in the pithed rat preparation" @default.
- W2022054435 cites W128969676 @default.
- W2022054435 cites W2048594503 @default.
- W2022054435 cites W2052325698 @default.
- W2022054435 doi "https://doi.org/10.1111/j.1476-5381.1983.tb10488.x" @default.
- W2022054435 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2044847" @default.
- W2022054435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6135473" @default.
- W2022054435 hasPublicationYear "1983" @default.
- W2022054435 type Work @default.
- W2022054435 sameAs 2022054435 @default.
- W2022054435 citedByCount "39" @default.
- W2022054435 crossrefType "journal-article" @default.
- W2022054435 hasAuthorship W2022054435A5056346637 @default.
- W2022054435 hasAuthorship W2022054435A5072251831 @default.
- W2022054435 hasBestOaLocation W20220544351 @default.
- W2022054435 hasConcept C126322002 @default.
- W2022054435 hasConcept C134018914 @default.
- W2022054435 hasConcept C170493617 @default.
- W2022054435 hasConcept C185592680 @default.
- W2022054435 hasConcept C2776885963 @default.
- W2022054435 hasConcept C2777842393 @default.
- W2022054435 hasConcept C2778539182 @default.
- W2022054435 hasConcept C2778938600 @default.
- W2022054435 hasConcept C2780648677 @default.
- W2022054435 hasConcept C71924100 @default.
- W2022054435 hasConcept C98274493 @default.
- W2022054435 hasConceptScore W2022054435C126322002 @default.
- W2022054435 hasConceptScore W2022054435C134018914 @default.
- W2022054435 hasConceptScore W2022054435C170493617 @default.
- W2022054435 hasConceptScore W2022054435C185592680 @default.
- W2022054435 hasConceptScore W2022054435C2776885963 @default.
- W2022054435 hasConceptScore W2022054435C2777842393 @default.
- W2022054435 hasConceptScore W2022054435C2778539182 @default.
- W2022054435 hasConceptScore W2022054435C2778938600 @default.
- W2022054435 hasConceptScore W2022054435C2780648677 @default.
- W2022054435 hasConceptScore W2022054435C71924100 @default.
- W2022054435 hasConceptScore W2022054435C98274493 @default.
- W2022054435 hasIssue "1" @default.
- W2022054435 hasLocation W20220544351 @default.
- W2022054435 hasLocation W20220544352 @default.
- W2022054435 hasLocation W20220544353 @default.
- W2022054435 hasLocation W20220544354 @default.
- W2022054435 hasOpenAccess W2022054435 @default.
- W2022054435 hasPrimaryLocation W20220544351 @default.
- W2022054435 hasRelatedWork W1785185999 @default.
- W2022054435 hasRelatedWork W1905562741 @default.
- W2022054435 hasRelatedWork W2007476630 @default.
- W2022054435 hasRelatedWork W2022054435 @default.
- W2022054435 hasRelatedWork W2022985373 @default.
- W2022054435 hasRelatedWork W2044729114 @default.
- W2022054435 hasRelatedWork W2052706297 @default.
- W2022054435 hasRelatedWork W2072738462 @default.
- W2022054435 hasRelatedWork W2281880853 @default.
- W2022054435 hasRelatedWork W3100008214 @default.
- W2022054435 hasVolume "79" @default.
- W2022054435 isParatext "false" @default.
- W2022054435 isRetracted "false" @default.
- W2022054435 magId "2022054435" @default.
- W2022054435 workType "article" @default.