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- W2022055130 abstract "An immunostaining procedure has been developed for the assay of the gangliotetraose gangliosides and sulfatide in cerebrospinal fluid. Gangliosides of the gangliotetraose series were individually determined with cholera toxin B-subunit (CT-B) and an anti CT-B monoclonal antibody after chromatography and sialidase hydrolysis to GM1 on high performance thin-layer plates. Sulfatide was determined by thin-layer chromatography using an anti-sulfatide antibody. The method was applied to normal cerebrospinal fluid from 20 adults and 30 children. The concentration of the gangliotetraose series gangliosides in adults varied from 100–300 nmol/l with a mean value of 230 ± 56 nmol/l. Corresponding values for sulfatide were 30–225 nmol/l and 140 ± 46 nmol/l. The values for gangliosides and sulfatide in children increased during development. The major gangliosides in cerebrospinal fluid of adults were GTlb and GDlb and in children GDla and GTlb." @default.
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- W2022055130 date "1996-09-01" @default.
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- W2022055130 title "Toxicity of antidepressant drugs: A comparative in vitro study" @default.
- W2022055130 doi "https://doi.org/10.1016/0924-977x(96)83021-5" @default.
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