Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022058186> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2022058186 endingPage "174" @default.
- W2022058186 startingPage "169" @default.
- W2022058186 abstract "Abstract A large number of flavonoids, mostly O‐glycosides, are found in foods of plant origin. The bound sugar moiety is known to influence their bioavailability. We examined here the effect of the nature of the sugar on the absorption of the glycosides. Four groups of rats (n=6) received a meal containing 20 mg of quercetin equivalents supplied as aglycone, quercetin 3‐glucoside, quercetin 3‐rhamnoside or rutin. Plasma were hydrolysed by a βglucuronidase/sulfatase and analyzed by HPLC coupled to UV detection at 370 nm. Four hours after the beginning of the meal, the quercetin metabolites present in plasma were identical in all groups but their total concentrations were quite different. With pure quercetin the circulating levels were 11.7± 1.8 μM, but this level was three fold higher when quercetin was supplied as quercetin 3‐glucoside (33.2± 3.5 μM). By contrast, the plasma concentrations of quercetin metabolites was quite low with the rutin meal (about 3 μM) and undetectable after the quercetin 3‐rhamnoside meal. These data suggest that the 3‐O‐glucosylation improves the absorption of quercetin in the small intestine, whereas the binding of a rhamnose or of a glucose‐rhamnose moiety to the aglycone markedly depressed its absorption. Additionnal experiments have shown that the higher plasma levels measured after the meal containing quercetin 3‐glucoside compared to quercetin were maintained throughout a 24 hour period following the meal. In conclusion, the nature of the glycosylation markedly influences the efficiency of quercetin absorption in rats. Quercetin 3‐glucose can be absorbed in the small intestine and is better absorbed than quercetin itself. By contrast, glycosides containing a rhamnose moiety could not be absorbed in the small intestine." @default.
- W2022058186 created "2016-06-24" @default.
- W2022058186 creator A5046686188 @default.
- W2022058186 creator A5059336112 @default.
- W2022058186 creator A5081075111 @default.
- W2022058186 creator A5081409044 @default.
- W2022058186 date "2000-01-01" @default.
- W2022058186 modified "2023-10-01" @default.
- W2022058186 title "Respective bioavailability of quercetin aglycone and its glycosides in a rat model" @default.
- W2022058186 cites W149486532 @default.
- W2022058186 cites W2038890001 @default.
- W2022058186 cites W2081187091 @default.
- W2022058186 cites W2119582385 @default.
- W2022058186 cites W2145047941 @default.
- W2022058186 doi "https://doi.org/10.1002/biof.5520120127" @default.
- W2022058186 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11216481" @default.
- W2022058186 hasPublicationYear "2000" @default.
- W2022058186 type Work @default.
- W2022058186 sameAs 2022058186 @default.
- W2022058186 citedByCount "122" @default.
- W2022058186 countsByYear W20220581862012 @default.
- W2022058186 countsByYear W20220581862013 @default.
- W2022058186 countsByYear W20220581862014 @default.
- W2022058186 countsByYear W20220581862015 @default.
- W2022058186 countsByYear W20220581862016 @default.
- W2022058186 countsByYear W20220581862017 @default.
- W2022058186 countsByYear W20220581862018 @default.
- W2022058186 countsByYear W20220581862019 @default.
- W2022058186 countsByYear W20220581862020 @default.
- W2022058186 countsByYear W20220581862021 @default.
- W2022058186 countsByYear W20220581862022 @default.
- W2022058186 countsByYear W20220581862023 @default.
- W2022058186 crossrefType "journal-article" @default.
- W2022058186 hasAuthorship W2022058186A5046686188 @default.
- W2022058186 hasAuthorship W2022058186A5059336112 @default.
- W2022058186 hasAuthorship W2022058186A5081075111 @default.
- W2022058186 hasAuthorship W2022058186A5081409044 @default.
- W2022058186 hasConcept C100817775 @default.
- W2022058186 hasConcept C142724271 @default.
- W2022058186 hasConcept C181389837 @default.
- W2022058186 hasConcept C185592680 @default.
- W2022058186 hasConcept C194671627 @default.
- W2022058186 hasConcept C204787440 @default.
- W2022058186 hasConcept C2775963812 @default.
- W2022058186 hasConcept C2778004101 @default.
- W2022058186 hasConcept C2779054382 @default.
- W2022058186 hasConcept C2779213145 @default.
- W2022058186 hasConcept C2779396346 @default.
- W2022058186 hasConcept C2781263971 @default.
- W2022058186 hasConcept C2781347565 @default.
- W2022058186 hasConcept C31903555 @default.
- W2022058186 hasConcept C43617362 @default.
- W2022058186 hasConcept C55493867 @default.
- W2022058186 hasConcept C71240020 @default.
- W2022058186 hasConcept C71924100 @default.
- W2022058186 hasConcept C86803240 @default.
- W2022058186 hasConcept C98274493 @default.
- W2022058186 hasConceptScore W2022058186C100817775 @default.
- W2022058186 hasConceptScore W2022058186C142724271 @default.
- W2022058186 hasConceptScore W2022058186C181389837 @default.
- W2022058186 hasConceptScore W2022058186C185592680 @default.
- W2022058186 hasConceptScore W2022058186C194671627 @default.
- W2022058186 hasConceptScore W2022058186C204787440 @default.
- W2022058186 hasConceptScore W2022058186C2775963812 @default.
- W2022058186 hasConceptScore W2022058186C2778004101 @default.
- W2022058186 hasConceptScore W2022058186C2779054382 @default.
- W2022058186 hasConceptScore W2022058186C2779213145 @default.
- W2022058186 hasConceptScore W2022058186C2779396346 @default.
- W2022058186 hasConceptScore W2022058186C2781263971 @default.
- W2022058186 hasConceptScore W2022058186C2781347565 @default.
- W2022058186 hasConceptScore W2022058186C31903555 @default.
- W2022058186 hasConceptScore W2022058186C43617362 @default.
- W2022058186 hasConceptScore W2022058186C55493867 @default.
- W2022058186 hasConceptScore W2022058186C71240020 @default.
- W2022058186 hasConceptScore W2022058186C71924100 @default.
- W2022058186 hasConceptScore W2022058186C86803240 @default.
- W2022058186 hasConceptScore W2022058186C98274493 @default.
- W2022058186 hasIssue "1-4" @default.
- W2022058186 hasLocation W20220581861 @default.
- W2022058186 hasLocation W20220581862 @default.
- W2022058186 hasLocation W20220581863 @default.
- W2022058186 hasOpenAccess W2022058186 @default.
- W2022058186 hasPrimaryLocation W20220581861 @default.
- W2022058186 hasRelatedWork W1571245707 @default.
- W2022058186 hasRelatedWork W2022058186 @default.
- W2022058186 hasRelatedWork W2047923693 @default.
- W2022058186 hasRelatedWork W2068080536 @default.
- W2022058186 hasRelatedWork W2105857789 @default.
- W2022058186 hasRelatedWork W2115139906 @default.
- W2022058186 hasRelatedWork W2163940672 @default.
- W2022058186 hasRelatedWork W2242032302 @default.
- W2022058186 hasRelatedWork W2605307718 @default.
- W2022058186 hasRelatedWork W3176921256 @default.
- W2022058186 hasVolume "12" @default.
- W2022058186 isParatext "false" @default.
- W2022058186 isRetracted "false" @default.
- W2022058186 magId "2022058186" @default.
- W2022058186 workType "article" @default.