FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022059294> ?p ?o ?g. }

• W2022059294 endingPage "319" @default.
• W2022059294 startingPage "307" @default.
• W2022059294 abstract "Inflammatory processes and the mechanisms by which they are initiated and controlled within the central nervous system (CNS) involve a vast array of cell types and molecules. One cell type believed to be involved in the control of inflammation in the CNS is the microglial cell. The TLD antibodies are a panel of monoclonal antibodies reactive to rat microglial antigens. One antibody from this panel, clone TLD-1A8A, is specific for antisecretory factor (ASF). ASF is a previously identified protein characterized as a potent inhibitor of enterotoxin-induced intestinal fluid secretion. Our results extend the function of this molecule to include the regulation of immune reactions. Administration of TLD-1A8A to T-cell proliferation or mixed leukocyte response assays resulted in increased proliferation of T cells. Flow cytometric analysis indicates that ASF is expressed on macrophages, B cells and dendritic cells, but not on T cells or granulocytes. Immunohistochemical analysis indicates that ASF is expressed by macrophages and cells of dendritic morphology in the spleen, thymus, lymph nodes, Peyer's patch, and in the perivascular area in the CNS. Furthermore, Western blot analysis indicates that ASF is expressed in many tissues including all secondary lymphoid organs. These data suggest that ASF may have a previously unsuspected role in regulating the immune system." @default.
• W2022059294 created "2016-06-24" @default.
• W2022059294 creator A5027637961 @default.
• W2022059294 creator A5086289654 @default.
• W2022059294 date "2004-03-01" @default.
• W2022059294 modified "2023-09-29" @default.
• W2022059294 title "Distribution and immunoregulatory properties of antisecretory factor" @default.
• W2022059294 cites W12673267 @default.
• W2022059294 cites W135952092 @default.
• W2022059294 cites W1532866158 @default.
• W2022059294 cites W1969992539 @default.
• W2022059294 cites W1984214223 @default.
• W2022059294 cites W1990405322 @default.
• W2022059294 cites W1993845422 @default.
• W2022059294 cites W2001430403 @default.
• W2022059294 cites W2008269957 @default.
• W2022059294 cites W2015037904 @default.
• W2022059294 cites W2022482220 @default.
• W2022059294 cites W2025911516 @default.
• W2022059294 cites W2037349488 @default.
• W2022059294 cites W2047143234 @default.
• W2022059294 cites W2048339215 @default.
• W2022059294 cites W2065411239 @default.
• W2022059294 cites W2074910450 @default.
• W2022059294 cites W2075118258 @default.
• W2022059294 cites W2078528638 @default.
• W2022059294 cites W2098646537 @default.
• W2022059294 cites W2127648442 @default.
• W2022059294 cites W2133415453 @default.
• W2022059294 cites W2158714788 @default.
• W2022059294 cites W2159746265 @default.
• W2022059294 cites W2191654227 @default.
• W2022059294 cites W4313315033 @default.
• W2022059294 doi "https://doi.org/10.1038/labinvest.3700036" @default.
• W2022059294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14767482" @default.
• W2022059294 hasPublicationYear "2004" @default.
• W2022059294 type Work @default.
• W2022059294 sameAs 2022059294 @default.
• W2022059294 citedByCount "37" @default.
• W2022059294 countsByYear W20220592942012 @default.
• W2022059294 countsByYear W20220592942013 @default.
• W2022059294 countsByYear W20220592942014 @default.
• W2022059294 countsByYear W20220592942015 @default.
• W2022059294 countsByYear W20220592942016 @default.
• W2022059294 countsByYear W20220592942017 @default.
• W2022059294 countsByYear W20220592942018 @default.
• W2022059294 countsByYear W20220592942019 @default.
• W2022059294 countsByYear W20220592942020 @default.
• W2022059294 countsByYear W20220592942022 @default.
• W2022059294 countsByYear W20220592942023 @default.
• W2022059294 crossrefType "journal-article" @default.
• W2022059294 hasAuthorship W2022059294A5027637961 @default.
• W2022059294 hasAuthorship W2022059294A5086289654 @default.
• W2022059294 hasBestOaLocation W20220592941 @default.
• W2022059294 hasConcept C134018914 @default.
• W2022059294 hasConcept C147483822 @default.
• W2022059294 hasConcept C153911025 @default.
• W2022059294 hasConcept C159654299 @default.
• W2022059294 hasConcept C203014093 @default.
• W2022059294 hasConcept C2776090121 @default.
• W2022059294 hasConcept C2776914184 @default.
• W2022059294 hasConcept C2779830541 @default.
• W2022059294 hasConcept C2780931953 @default.
• W2022059294 hasConcept C3753494 @default.
• W2022059294 hasConcept C49039625 @default.
• W2022059294 hasConcept C542903549 @default.
• W2022059294 hasConcept C54355233 @default.
• W2022059294 hasConcept C552990157 @default.
• W2022059294 hasConcept C67662055 @default.
• W2022059294 hasConcept C81089528 @default.
• W2022059294 hasConcept C86803240 @default.
• W2022059294 hasConcept C8891405 @default.
• W2022059294 hasConcept C95444343 @default.
• W2022059294 hasConceptScore W2022059294C134018914 @default.
• W2022059294 hasConceptScore W2022059294C147483822 @default.
• W2022059294 hasConceptScore W2022059294C153911025 @default.
• W2022059294 hasConceptScore W2022059294C159654299 @default.
• W2022059294 hasConceptScore W2022059294C203014093 @default.
• W2022059294 hasConceptScore W2022059294C2776090121 @default.
• W2022059294 hasConceptScore W2022059294C2776914184 @default.
• W2022059294 hasConceptScore W2022059294C2779830541 @default.
• W2022059294 hasConceptScore W2022059294C2780931953 @default.
• W2022059294 hasConceptScore W2022059294C3753494 @default.
• W2022059294 hasConceptScore W2022059294C49039625 @default.
• W2022059294 hasConceptScore W2022059294C542903549 @default.
• W2022059294 hasConceptScore W2022059294C54355233 @default.
• W2022059294 hasConceptScore W2022059294C552990157 @default.
• W2022059294 hasConceptScore W2022059294C67662055 @default.
• W2022059294 hasConceptScore W2022059294C81089528 @default.
• W2022059294 hasConceptScore W2022059294C86803240 @default.
• W2022059294 hasConceptScore W2022059294C8891405 @default.
• W2022059294 hasConceptScore W2022059294C95444343 @default.
• W2022059294 hasIssue "3" @default.
• W2022059294 hasLocation W20220592941 @default.
• W2022059294 hasLocation W20220592942 @default.
• W2022059294 hasOpenAccess W2022059294 @default.
• W2022059294 hasPrimaryLocation W20220592941 @default.
• W2022059294 hasRelatedWork W1997716688 @default.

• next