Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022060293> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2022060293 endingPage "323" @default.
- W2022060293 startingPage "318" @default.
- W2022060293 abstract "We investigated the relation between IgE reactive with histamine-releasing factor (HRF) and clinical status in patients with asthma or rhinitis. Sera were used to passively sensitize purified, lactic-acid treated basophils. IgE-independent HRF due to chemokines was removed from mononuclear cell supernatants with heparin-Sepharose. IgE-dependent HRF was determined by measuring the increase in histamine release between 1 min and 60 min, which was designated delta HRF. HRF-reactive IgE was demonstrable in nine of 18 patients with allergic asthma, three of 19 patients with nonallergic asthma, five of 17 patients with allergic rhinitis, and none of 19 control patients. The presence of HRF-reactive IgE was associated with: (1) IgE to inhalant allergens; 40% of radioallergosorbent test (RAST)-positive individuals versus 8% of RAST-negative individuals were positive (OR = 7.8, p < 0.005); (2) bronchial sensitivity to histamine in all asthmatic patients (geometric mean PC20: 1.50 versus 0.51 mg/ml; p < 0.005); and (3) bronchial sensitivity to histamine in allergic asthmatic patients (geometric mean PC20: 1.27 versus 0.37 mg/ml, p < 0.02). These findings support the hypothesis that IgE-dependent HRF might contribute to the chronic allergic reaction." @default.
- W2022060293 created "2016-06-24" @default.
- W2022060293 creator A5001880561 @default.
- W2022060293 creator A5021020646 @default.
- W2022060293 creator A5032605291 @default.
- W2022060293 creator A5062229157 @default.
- W2022060293 creator A5073842398 @default.
- W2022060293 creator A5090630130 @default.
- W2022060293 creator A5090955045 @default.
- W2022060293 date "1996-08-01" @default.
- W2022060293 modified "2023-10-14" @default.
- W2022060293 title "Reactivity to IgE-dependent histamine-releasing activity in asthma or rhinitis." @default.
- W2022060293 doi "https://doi.org/10.1164/ajrccm.154.2.8756800" @default.
- W2022060293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8756800" @default.
- W2022060293 hasPublicationYear "1996" @default.
- W2022060293 type Work @default.
- W2022060293 sameAs 2022060293 @default.
- W2022060293 citedByCount "8" @default.
- W2022060293 countsByYear W20220602932013 @default.
- W2022060293 countsByYear W20220602932014 @default.
- W2022060293 crossrefType "journal-article" @default.
- W2022060293 hasAuthorship W2022060293A5001880561 @default.
- W2022060293 hasAuthorship W2022060293A5021020646 @default.
- W2022060293 hasAuthorship W2022060293A5032605291 @default.
- W2022060293 hasAuthorship W2022060293A5062229157 @default.
- W2022060293 hasAuthorship W2022060293A5073842398 @default.
- W2022060293 hasAuthorship W2022060293A5090630130 @default.
- W2022060293 hasAuthorship W2022060293A5090955045 @default.
- W2022060293 hasConcept C1122143 @default.
- W2022060293 hasConcept C126322002 @default.
- W2022060293 hasConcept C141105273 @default.
- W2022060293 hasConcept C159654299 @default.
- W2022060293 hasConcept C203014093 @default.
- W2022060293 hasConcept C207480886 @default.
- W2022060293 hasConcept C2776042228 @default.
- W2022060293 hasConcept C2780451875 @default.
- W2022060293 hasConcept C71924100 @default.
- W2022060293 hasConceptScore W2022060293C1122143 @default.
- W2022060293 hasConceptScore W2022060293C126322002 @default.
- W2022060293 hasConceptScore W2022060293C141105273 @default.
- W2022060293 hasConceptScore W2022060293C159654299 @default.
- W2022060293 hasConceptScore W2022060293C203014093 @default.
- W2022060293 hasConceptScore W2022060293C207480886 @default.
- W2022060293 hasConceptScore W2022060293C2776042228 @default.
- W2022060293 hasConceptScore W2022060293C2780451875 @default.
- W2022060293 hasConceptScore W2022060293C71924100 @default.
- W2022060293 hasIssue "2" @default.
- W2022060293 hasLocation W20220602931 @default.
- W2022060293 hasLocation W20220602932 @default.
- W2022060293 hasOpenAccess W2022060293 @default.
- W2022060293 hasPrimaryLocation W20220602931 @default.
- W2022060293 hasRelatedWork W157857562 @default.
- W2022060293 hasRelatedWork W1964408459 @default.
- W2022060293 hasRelatedWork W1965983568 @default.
- W2022060293 hasRelatedWork W2072515372 @default.
- W2022060293 hasRelatedWork W2331727149 @default.
- W2022060293 hasRelatedWork W2412068494 @default.
- W2022060293 hasRelatedWork W2412813622 @default.
- W2022060293 hasRelatedWork W2414899500 @default.
- W2022060293 hasRelatedWork W2945931813 @default.
- W2022060293 hasRelatedWork W4241659254 @default.
- W2022060293 hasVolume "154" @default.
- W2022060293 isParatext "false" @default.
- W2022060293 isRetracted "false" @default.
- W2022060293 magId "2022060293" @default.
- W2022060293 workType "article" @default.