Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022060430> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2022060430 endingPage "438" @default.
- W2022060430 startingPage "432" @default.
- W2022060430 abstract "Hyperlactatemia is a frequent complication of sepsis. We investigated the effect of pentoxifylline on plasma lactate concentrations and lactate release by epitrochlearis incubated in vitro following intravenous injection of Escherichia coli. Plasma lactate concentrations were elevated on day 2 postinfection and remained elevated for at least another 4 days. Lactate production by incubated epitrochlearis was not increased in septic rats on day 2 postinfection, and lactate production from muscles incubated with insulin (2 nM) or insulin-like growth factor-1, (10 nM) was similar in control and septic rats. On day 6 postinfection, lactate production was augmented 1.8-fold in muscles from septic rats and both insulin and IGF-I caused an exaggerated stimulation of lactate production compared with control. Pentoxifylline decreased plasma TNF concentrations 100-fold following injection of bacteria, and prevented the sepsis-induced hypertactatemia and increase in lactate production by incubated muscles in presence or absence of insulin or IGF-I. Thus, pentoxifylline prevented the sepsis-induced abnormalities in skeletal muscle lactate production and plasma lactate concentrations." @default.
- W2022060430 created "2016-06-24" @default.
- W2022060430 creator A5000236956 @default.
- W2022060430 creator A5032556937 @default.
- W2022060430 creator A5038497798 @default.
- W2022060430 creator A5043660331 @default.
- W2022060430 creator A5076146157 @default.
- W2022060430 creator A5078093466 @default.
- W2022060430 date "1997-06-01" @default.
- W2022060430 modified "2023-10-08" @default.
- W2022060430 title "MODULATION OF SKELETAL MUSCLE LACTATE METABOLISM FOLLOWING BACTEREMIA BY INSULIN OR INSULIN-LIKE GROWTH FACTOR-I" @default.
- W2022060430 doi "https://doi.org/10.1097/00024382-199706000-00008" @default.
- W2022060430 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9185244" @default.
- W2022060430 hasPublicationYear "1997" @default.
- W2022060430 type Work @default.
- W2022060430 sameAs 2022060430 @default.
- W2022060430 citedByCount "16" @default.
- W2022060430 countsByYear W20220604302015 @default.
- W2022060430 crossrefType "journal-article" @default.
- W2022060430 hasAuthorship W2022060430A5000236956 @default.
- W2022060430 hasAuthorship W2022060430A5032556937 @default.
- W2022060430 hasAuthorship W2022060430A5038497798 @default.
- W2022060430 hasAuthorship W2022060430A5043660331 @default.
- W2022060430 hasAuthorship W2022060430A5076146157 @default.
- W2022060430 hasAuthorship W2022060430A5078093466 @default.
- W2022060430 hasBestOaLocation W20220604301 @default.
- W2022060430 hasConcept C126322002 @default.
- W2022060430 hasConcept C134018914 @default.
- W2022060430 hasConcept C185592680 @default.
- W2022060430 hasConcept C2775920511 @default.
- W2022060430 hasConcept C2778384902 @default.
- W2022060430 hasConcept C2779306644 @default.
- W2022060430 hasConcept C2779959927 @default.
- W2022060430 hasConcept C2909186138 @default.
- W2022060430 hasConcept C523546767 @default.
- W2022060430 hasConcept C54355233 @default.
- W2022060430 hasConcept C62231903 @default.
- W2022060430 hasConcept C71924100 @default.
- W2022060430 hasConcept C86803240 @default.
- W2022060430 hasConceptScore W2022060430C126322002 @default.
- W2022060430 hasConceptScore W2022060430C134018914 @default.
- W2022060430 hasConceptScore W2022060430C185592680 @default.
- W2022060430 hasConceptScore W2022060430C2775920511 @default.
- W2022060430 hasConceptScore W2022060430C2778384902 @default.
- W2022060430 hasConceptScore W2022060430C2779306644 @default.
- W2022060430 hasConceptScore W2022060430C2779959927 @default.
- W2022060430 hasConceptScore W2022060430C2909186138 @default.
- W2022060430 hasConceptScore W2022060430C523546767 @default.
- W2022060430 hasConceptScore W2022060430C54355233 @default.
- W2022060430 hasConceptScore W2022060430C62231903 @default.
- W2022060430 hasConceptScore W2022060430C71924100 @default.
- W2022060430 hasConceptScore W2022060430C86803240 @default.
- W2022060430 hasIssue "6" @default.
- W2022060430 hasLocation W20220604301 @default.
- W2022060430 hasLocation W20220604302 @default.
- W2022060430 hasLocation W20220604303 @default.
- W2022060430 hasOpenAccess W2022060430 @default.
- W2022060430 hasPrimaryLocation W20220604301 @default.
- W2022060430 hasRelatedWork W1982295810 @default.
- W2022060430 hasRelatedWork W2104946684 @default.
- W2022060430 hasRelatedWork W2119416234 @default.
- W2022060430 hasRelatedWork W2302971467 @default.
- W2022060430 hasRelatedWork W2970552693 @default.
- W2022060430 hasRelatedWork W3140396627 @default.
- W2022060430 hasRelatedWork W4231627201 @default.
- W2022060430 hasRelatedWork W4291017766 @default.
- W2022060430 hasRelatedWork W4293249210 @default.
- W2022060430 hasRelatedWork W2103302820 @default.
- W2022060430 hasVolume "7" @default.
- W2022060430 isParatext "false" @default.
- W2022060430 isRetracted "false" @default.
- W2022060430 magId "2022060430" @default.
- W2022060430 workType "article" @default.