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- W2022065887 abstract "OBJECTIVE: To investigate the effect of a daily soy supplement versus a casein placebo on change in dietary macronutrients and trace elements in postmenopausal women. DESIGN: Randomized, double-blinded, placebo-controlled trial. MATERIALS AND METHODS: Thirty-nine postmenopausal women were randomized for 3 months to a supplement containing either soy protein plus isoflavones (20 g protein plus 120 mg isoflavones) versus a casein placebo without isoflavones as part of a weight-maintenance diet. At baseline and at follow up, a 4-day food record was collected for each subject and analyzed using the Nutrition Data System for Research software. Medians and interquartile ranges were determined for values at baseline and follow up, and the changes between soy and placebo groups over time were calculated for total dietary fat, carbohydrate, and protein; 18 amino acids; percent calories from saturated, monounsaturated, and polyunsaturated fatty acids; total, soluble, and insoluble dietary fiber; and 9 trace metals. We evaluated the significance of the change in these measures between soy and placebo using the Wilcoxon rank sum test or t-tests, as appropriate, with statistical significance set at p<0.05. RESULTS: Groups were similar at baseline. Soy supplementation did not affect changes in total dietary fat, carbohydrate or protein, or in any amino acid, dietary fiber, or trace mineral compared to placebo. However, the soy supplement reduced the percent calories from saturated fatty acids compared to placebo (p=0.0324), with a trend toward increasing the percent calories from polyunsaturated fatty acids (p=0.0804). Specifically, caprylic acid, a saturated fatty acid, was reduced by the supplement compared to placebo (p=0.0288). CONCLUSION: As part of a weight maintenance diet for postmenopausal women, soy supplementation may promote cardiovascular health by reducing the percent calories from saturated fatty acids." @default.
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- W2022065887 date "2010-09-01" @default.
- W2022065887 modified "2023-09-27" @default.
- W2022065887 title "Effect of soy supplementation on dietary macronutrients and trace elements in postmenopausal women" @default.
- W2022065887 doi "https://doi.org/10.1016/j.fertnstert.2010.07.355" @default.
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