Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022068078> ?p ?o ?g. }
- W2022068078 abstract "Plant immune responses against biotrophic pathogens are regulated by the signaling hormone salicylic acid (SA). SA establishes immunity by regulating a variety of cellular processes, including programmed cell death (PCD) to isolate and kill invading pathogens, and development of systemic acquired resistance (SAR) which provides long-lasting, broad-spectrum resistance throughout the plant. Central to these processes is post-translational modification of SA-regulated signaling proteins by ubiquitination, i.e. the covalent addition of small ubiquitin proteins. Emerging evidence indicates SA-induced protein ubiquitination is largely orchestrated by Cullin-RING ligases (CRLs), which recruit specific substrates for ubiquitination using interchangeable adaptors. Ligation of ubiquitin chains interlinked at lysine 48 leads to substrate degradation by the 26S proteasome. Here we discuss how CRL-mediated degradation of both nucleotide-binding/leucine-rich repeat domain containing (NLR) immune receptors and SA-induced transcription regulators are critical for functional PCD and SAR responses, respectively. By placing these recent findings in context of knowledge gained in other eukaryotic model species, we highlight potential alternative roles for processive ubiquitination in regulating the activity of SA-mediated immune responses." @default.
- W2022068078 created "2016-06-24" @default.
- W2022068078 creator A5063016242 @default.
- W2022068078 creator A5080033417 @default.
- W2022068078 date "2015-03-13" @default.
- W2022068078 modified "2023-10-17" @default.
- W2022068078 title "Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling" @default.
- W2022068078 cites W1531719897 @default.
- W2022068078 cites W1559065834 @default.
- W2022068078 cites W1835605130 @default.
- W2022068078 cites W1875904515 @default.
- W2022068078 cites W1942665378 @default.
- W2022068078 cites W1954742316 @default.
- W2022068078 cites W1964937122 @default.
- W2022068078 cites W1965995197 @default.
- W2022068078 cites W1966975589 @default.
- W2022068078 cites W1969416557 @default.
- W2022068078 cites W1970078607 @default.
- W2022068078 cites W1974177536 @default.
- W2022068078 cites W1980168194 @default.
- W2022068078 cites W1981414739 @default.
- W2022068078 cites W1982692519 @default.
- W2022068078 cites W1985562398 @default.
- W2022068078 cites W1986921906 @default.
- W2022068078 cites W1987003587 @default.
- W2022068078 cites W1988031203 @default.
- W2022068078 cites W1988313771 @default.
- W2022068078 cites W1988351397 @default.
- W2022068078 cites W1993550226 @default.
- W2022068078 cites W2000287507 @default.
- W2022068078 cites W2002821316 @default.
- W2022068078 cites W2007573576 @default.
- W2022068078 cites W2012326746 @default.
- W2022068078 cites W2013339424 @default.
- W2022068078 cites W2018909107 @default.
- W2022068078 cites W2019779457 @default.
- W2022068078 cites W2021107644 @default.
- W2022068078 cites W2021731617 @default.
- W2022068078 cites W2023183725 @default.
- W2022068078 cites W2025983519 @default.
- W2022068078 cites W2026715418 @default.
- W2022068078 cites W2029330932 @default.
- W2022068078 cites W2032555227 @default.
- W2022068078 cites W2033427788 @default.
- W2022068078 cites W2038208040 @default.
- W2022068078 cites W2038852478 @default.
- W2022068078 cites W2039974624 @default.
- W2022068078 cites W2041119476 @default.
- W2022068078 cites W2047233829 @default.
- W2022068078 cites W2048966465 @default.
- W2022068078 cites W2050662242 @default.
- W2022068078 cites W2056712097 @default.
- W2022068078 cites W2059321776 @default.
- W2022068078 cites W2073224077 @default.
- W2022068078 cites W2076640479 @default.
- W2022068078 cites W2078197564 @default.
- W2022068078 cites W2080174206 @default.
- W2022068078 cites W2081545299 @default.
- W2022068078 cites W2085196189 @default.
- W2022068078 cites W2090677679 @default.
- W2022068078 cites W2092726795 @default.
- W2022068078 cites W2096881442 @default.
- W2022068078 cites W2097202036 @default.
- W2022068078 cites W2098476552 @default.
- W2022068078 cites W2099400045 @default.
- W2022068078 cites W2101264892 @default.
- W2022068078 cites W2104990469 @default.
- W2022068078 cites W2107949774 @default.
- W2022068078 cites W2109210300 @default.
- W2022068078 cites W2109535147 @default.
- W2022068078 cites W2110311890 @default.
- W2022068078 cites W2112528524 @default.
- W2022068078 cites W2116293159 @default.
- W2022068078 cites W2120470126 @default.
- W2022068078 cites W2122268984 @default.
- W2022068078 cites W2123355136 @default.
- W2022068078 cites W2125105859 @default.
- W2022068078 cites W2126302335 @default.
- W2022068078 cites W2127120813 @default.
- W2022068078 cites W2128928858 @default.
- W2022068078 cites W2130761076 @default.
- W2022068078 cites W2131575598 @default.
- W2022068078 cites W2134485426 @default.
- W2022068078 cites W2135776390 @default.
- W2022068078 cites W2137007437 @default.
- W2022068078 cites W2137136072 @default.
- W2022068078 cites W2137770315 @default.
- W2022068078 cites W2138693996 @default.
- W2022068078 cites W2139170657 @default.
- W2022068078 cites W2139987839 @default.
- W2022068078 cites W2144281054 @default.
- W2022068078 cites W2146052432 @default.
- W2022068078 cites W2146648532 @default.
- W2022068078 cites W2147321004 @default.
- W2022068078 cites W2147917253 @default.
- W2022068078 cites W2153408508 @default.
- W2022068078 cites W2155080972 @default.
- W2022068078 cites W2156219697 @default.
- W2022068078 cites W2156301059 @default.
- W2022068078 cites W2158367220 @default.