FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022071767> ?p ?o ?g. }

• W2022071767 endingPage "2712" @default.
• W2022071767 startingPage "2703" @default.
• W2022071767 abstract "Background. Treatment of cancer with multiple-drug chemotherapy regimens or radiation therapy can cause either temporary azoospermia of various durations or permanent azoospermia in young men. Methods. To identify which drugs in which doses contribute to long-term or permanent azoospermia, semen analyses were done on patients with Ewing and soft tissue sarcomas before, during, and after treatment with either CYADIC (cyclophosphamide, doxorubicin, and dacarbazine), or CYVADIC (vincristine added to CYADIC). Some patients also received other drugs or radiation therapy. Results. From pretreatment levels that were similar to those of control subjects, sperm production declined to azoospermia within 4 months of treatment. Sperm production returned in some patients after treatment; 40% of men recovered to normospermic levels by 5 years after treatment. Few patients showed continued recovery of sperm production after that time. The cumulative dose of cyclophosphamide was the most significant determinant of recovery to normospermic levels; approximately 70% of those who had received doses less than 7.5 g/m2 (median, 4.1 g/m2) recovered, but only 10% recovered when doses exceeded 7.5 g/m2. Conclusions. Thus, a risk of permanent sterility is associated with the use of the CYADIC and CYVADIC regimens in young men, especially when the cumulative dose of cyclophosphamide is greater than 7.5 mg/m2." @default.
• W2022071767 created "2016-06-24" @default.
• W2022071767 creator A5038348446 @default.
• W2022071767 creator A5075937677 @default.
• W2022071767 creator A5078857969 @default.
• W2022071767 creator A5087500960 @default.
• W2022071767 creator A5090076620 @default.
• W2022071767 date "1992-12-01" @default.
• W2022071767 modified "2023-10-16" @default.
• W2022071767 title "Impact of cyclophosphamide on long-term reduction in sperm count in men treated with combination chemotherapy for ewing and soft tissue sarcomas" @default.
• W2022071767 cites W120921079 @default.
• W2022071767 cites W1552192416 @default.
• W2022071767 cites W1975487499 @default.
• W2022071767 cites W1976686772 @default.
• W2022071767 cites W1978723594 @default.
• W2022071767 cites W1988783532 @default.
• W2022071767 cites W1991607336 @default.
• W2022071767 cites W1996729973 @default.
• W2022071767 cites W2017308251 @default.
• W2022071767 cites W2035026242 @default.
• W2022071767 cites W2053941291 @default.
• W2022071767 cites W2058655763 @default.
• W2022071767 cites W2065704766 @default.
• W2022071767 cites W2084182644 @default.
• W2022071767 cites W2085671699 @default.
• W2022071767 cites W2094898025 @default.
• W2022071767 cites W2104604416 @default.
• W2022071767 cites W2121174803 @default.
• W2022071767 cites W2140563146 @default.
• W2022071767 cites W2170900038 @default.
• W2022071767 cites W2176957466 @default.
• W2022071767 cites W2206556148 @default.
• W2022071767 cites W2246556650 @default.
• W2022071767 cites W2272466782 @default.
• W2022071767 cites W2403233854 @default.
• W2022071767 cites W2415791092 @default.
• W2022071767 cites W2417900912 @default.
• W2022071767 cites W32437444 @default.
• W2022071767 cites W4243745865 @default.
• W2022071767 doi "https://doi.org/10.1002/1097-0142(19921201)70:11<2703::aid-cncr2820701123>3.0.co;2-x" @default.
• W2022071767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1423201" @default.
• W2022071767 hasPublicationYear "1992" @default.
• W2022071767 type Work @default.
• W2022071767 sameAs 2022071767 @default.
• W2022071767 citedByCount "218" @default.
• W2022071767 countsByYear W20220717672012 @default.
• W2022071767 countsByYear W20220717672013 @default.
• W2022071767 countsByYear W20220717672014 @default.
• W2022071767 countsByYear W20220717672015 @default.
• W2022071767 countsByYear W20220717672016 @default.
• W2022071767 countsByYear W20220717672017 @default.
• W2022071767 countsByYear W20220717672018 @default.
• W2022071767 countsByYear W20220717672019 @default.
• W2022071767 countsByYear W20220717672020 @default.
• W2022071767 countsByYear W20220717672021 @default.
• W2022071767 countsByYear W20220717672022 @default.
• W2022071767 countsByYear W20220717672023 @default.
• W2022071767 crossrefType "journal-article" @default.
• W2022071767 hasAuthorship W2022071767A5038348446 @default.
• W2022071767 hasAuthorship W2022071767A5075937677 @default.
• W2022071767 hasAuthorship W2022071767A5078857969 @default.
• W2022071767 hasAuthorship W2022071767A5087500960 @default.
• W2022071767 hasAuthorship W2022071767A5090076620 @default.
• W2022071767 hasBestOaLocation W20220717671 @default.
• W2022071767 hasConcept C126322002 @default.
• W2022071767 hasConcept C126894567 @default.
• W2022071767 hasConcept C141071460 @default.
• W2022071767 hasConcept C151032500 @default.
• W2022071767 hasConcept C16685009 @default.
• W2022071767 hasConcept C2776694085 @default.
• W2022071767 hasConcept C2776755627 @default.
• W2022071767 hasConcept C2777420699 @default.
• W2022071767 hasConcept C2777688143 @default.
• W2022071767 hasConcept C2779234561 @default.
• W2022071767 hasConcept C2779429289 @default.
• W2022071767 hasConcept C2780964509 @default.
• W2022071767 hasConcept C2781087480 @default.
• W2022071767 hasConcept C2781303535 @default.
• W2022071767 hasConcept C509974204 @default.
• W2022071767 hasConcept C54355233 @default.
• W2022071767 hasConcept C71924100 @default.
• W2022071767 hasConcept C86803240 @default.
• W2022071767 hasConceptScore W2022071767C126322002 @default.
• W2022071767 hasConceptScore W2022071767C126894567 @default.
• W2022071767 hasConceptScore W2022071767C141071460 @default.
• W2022071767 hasConceptScore W2022071767C151032500 @default.
• W2022071767 hasConceptScore W2022071767C16685009 @default.
• W2022071767 hasConceptScore W2022071767C2776694085 @default.
• W2022071767 hasConceptScore W2022071767C2776755627 @default.
• W2022071767 hasConceptScore W2022071767C2777420699 @default.
• W2022071767 hasConceptScore W2022071767C2777688143 @default.
• W2022071767 hasConceptScore W2022071767C2779234561 @default.
• W2022071767 hasConceptScore W2022071767C2779429289 @default.
• W2022071767 hasConceptScore W2022071767C2780964509 @default.
• W2022071767 hasConceptScore W2022071767C2781087480 @default.
• W2022071767 hasConceptScore W2022071767C2781303535 @default.
• W2022071767 hasConceptScore W2022071767C509974204 @default.
• W2022071767 hasConceptScore W2022071767C54355233 @default.

• next