FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022071798> ?p ?o ?g. }

• W2022071798 endingPage "181" @default.
• W2022071798 startingPage "168" @default.
• W2022071798 abstract "Although most projection neurons in the primate dorsal lateral geniculate nucleus (dLGN) target striate cortex (V1), a small number project instead to extrastriate visual areas and have been suggested to play a role in the preserved vision (blindsight) that survives damage to V1. Moreover, the distribution of dLGN cells projecting to extrastriate bears a striking similarity to that of neurons that stain for calbindin D-28K (Cal), a calcium-binding protein involved in regulating neuronal excitability and considered a marker for the koniocellular or K pathway of geniculocortical processing. In these studies, we used double-labeling techniques to examine whether Cal content characterizes all or a subset of neurons making up the geniculo-extrastriate pathway in normal macaque monkeys. After injections of cholera toxin B-subunit into the prelunate gyrus, the proportion of retrogradely labeled neurons in the dLGN that were also immunoreactive for Cal varied from less than 40% to over 80%, indicating that only a subset of the geniculo-extrastriate projection falls within the K pathway as defined by Cal content. Analysis of the injected territories indicated that identity of the extrastriate cortical target may be systematically related to Cal content in the geniculo-extrastriate projection. To see whether the Cal-immunoreactive dLGN population might potentially play a role in preserved vision after V1 damage, we also examined the dLGN of a macaque that had sustained a lesion of V1 in infancy and survived until 4 years. In this animal, large, intensely Cal-immunoreactive neurons were found scattered throughout the otherwise degenerated dLGN zones and made up over 95% of the identifiable remaining neurons. The results support an emerging view that the macaque koniocellular system is highly heterogeneous in nature and also suggest that Cal content may be a critical feature of the pathway by which visual information reaches extrastriate cortex in the absence of V1." @default.
• W2022071798 created "2016-06-24" @default.
• W2022071798 creator A5004298851 @default.
• W2022071798 creator A5027082907 @default.
• W2022071798 creator A5035861274 @default.
• W2022071798 creator A5043602782 @default.
• W2022071798 date "2001-01-01" @default.
• W2022071798 modified "2023-10-18" @default.
• W2022071798 title "Calbindin immunoreactivity in the geniculo-extrastriate system of the macaque: Implications for heterogeneity in the koniocellular pathway and recovery from cortical damage" @default.
• W2022071798 cites W138158585 @default.
• W2022071798 cites W1757208289 @default.
• W2022071798 cites W1966229684 @default.
• W2022071798 cites W1970652048 @default.
• W2022071798 cites W1973410327 @default.
• W2022071798 cites W1973593131 @default.
• W2022071798 cites W1975018267 @default.
• W2022071798 cites W1980263527 @default.
• W2022071798 cites W1982280357 @default.
• W2022071798 cites W1982292803 @default.
• W2022071798 cites W1982921062 @default.
• W2022071798 cites W1985077356 @default.
• W2022071798 cites W1989486367 @default.
• W2022071798 cites W1989725457 @default.
• W2022071798 cites W1990083315 @default.
• W2022071798 cites W1990454417 @default.
• W2022071798 cites W1990576245 @default.
• W2022071798 cites W1991441973 @default.
• W2022071798 cites W1992173856 @default.
• W2022071798 cites W1993879353 @default.
• W2022071798 cites W1993972294 @default.
• W2022071798 cites W1997037178 @default.
• W2022071798 cites W1997317621 @default.
• W2022071798 cites W1997408563 @default.
• W2022071798 cites W2004437358 @default.
• W2022071798 cites W2004672365 @default.
• W2022071798 cites W2009406781 @default.
• W2022071798 cites W2019150489 @default.
• W2022071798 cites W2019543782 @default.
• W2022071798 cites W2023227660 @default.
• W2022071798 cites W2023349196 @default.
• W2022071798 cites W2026078246 @default.
• W2022071798 cites W2041037585 @default.
• W2022071798 cites W2069538091 @default.
• W2022071798 cites W2078243293 @default.
• W2022071798 cites W2080876520 @default.
• W2022071798 cites W2086347584 @default.
• W2022071798 cites W2092010621 @default.
• W2022071798 cites W2097462803 @default.
• W2022071798 cites W2097542264 @default.
• W2022071798 cites W2101122970 @default.
• W2022071798 cites W2110177403 @default.
• W2022071798 cites W2116215865 @default.
• W2022071798 cites W2119760223 @default.
• W2022071798 cites W2123363219 @default.
• W2022071798 cites W2140328151 @default.
• W2022071798 cites W2140480060 @default.
• W2022071798 cites W2144208579 @default.
• W2022071798 cites W2145439642 @default.
• W2022071798 cites W2154050646 @default.
• W2022071798 cites W2156625231 @default.
• W2022071798 cites W2161117098 @default.
• W2022071798 cites W2162152644 @default.
• W2022071798 cites W2416044935 @default.
• W2022071798 cites W4229627221 @default.
• W2022071798 cites W4252300605 @default.
• W2022071798 doi "https://doi.org/10.1002/1096-9861(20010305)431:2<168::aid-cne1063>3.0.co;2-n" @default.
• W2022071798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11169998" @default.
• W2022071798 hasPublicationYear "2001" @default.
• W2022071798 type Work @default.
• W2022071798 sameAs 2022071798 @default.
• W2022071798 citedByCount "47" @default.
• W2022071798 countsByYear W20220717982012 @default.
• W2022071798 countsByYear W20220717982013 @default.
• W2022071798 countsByYear W20220717982014 @default.
• W2022071798 countsByYear W20220717982015 @default.
• W2022071798 countsByYear W20220717982016 @default.
• W2022071798 countsByYear W20220717982017 @default.
• W2022071798 countsByYear W20220717982018 @default.
• W2022071798 countsByYear W20220717982019 @default.
• W2022071798 countsByYear W20220717982020 @default.
• W2022071798 countsByYear W20220717982021 @default.
• W2022071798 countsByYear W20220717982022 @default.
• W2022071798 countsByYear W20220717982023 @default.
• W2022071798 crossrefType "journal-article" @default.
• W2022071798 hasAuthorship W2022071798A5004298851 @default.
• W2022071798 hasAuthorship W2022071798A5027082907 @default.
• W2022071798 hasAuthorship W2022071798A5035861274 @default.
• W2022071798 hasAuthorship W2022071798A5043602782 @default.
• W2022071798 hasConcept C119088629 @default.
• W2022071798 hasConcept C121731113 @default.
• W2022071798 hasConcept C169760540 @default.
• W2022071798 hasConcept C203014093 @default.
• W2022071798 hasConcept C204232928 @default.
• W2022071798 hasConcept C26265296 @default.
• W2022071798 hasConcept C2778950215 @default.
• W2022071798 hasConcept C2779345533 @default.
• W2022071798 hasConcept C2780217011 @default.
• W2022071798 hasConcept C2908647359 @default.

• next