FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022081023> ?p ?o ?g. }

• W2022081023 endingPage "771" @default.
• W2022081023 startingPage "765" @default.
• W2022081023 abstract "The characteristic chromosomal translocations that occur in certain human malignancies offer opportunities to understand how two gene systems can affect one another when they are accidentally juxtaposed. In the case of Burkitt lymphoma, such a translocation joins the cellular oncogene, c-myc, to a region encoding one of the immunoglobulin genes. In at least one example, the coding sequence of the rearranged c-myc gene is identical to that of the normal gene, implying that the gene must be quantitatively, rather than qualitatively, altered in its expression if it is to play a role in transformation. One might expect to find the rearranged c-myc gene in a configuration that would allow it to take advantage of one of the known immunoglobulin promoters or enhancer elements. However, the rearranged c-myc gene is often placed so that it can utilize neither of these structures. Since the level of c-myc messenger RNA is often elevated in Burkitt cells, the translocation may lead to a deregulation of the c-myc gene. Further, since the normal allele in a Burkitt cell is often transcriptionally silent in the presence of a rearranged allele, a model for c-myc regulation is suggested that involves a trans-acting negative control element that might use as its target a highly conserved portion of the c-myc gene encoding two discrete transcriptional promoters." @default.
• W2022081023 created "2016-06-24" @default.
• W2022081023 creator A5010721531 @default.
• W2022081023 creator A5050156267 @default.
• W2022081023 creator A5054037083 @default.
• W2022081023 creator A5070752173 @default.
• W2022081023 creator A5075534723 @default.
• W2022081023 creator A5078971738 @default.
• W2022081023 creator A5080451187 @default.
• W2022081023 creator A5085778554 @default.
• W2022081023 date "1983-11-18" @default.
• W2022081023 modified "2023-10-16" @default.
• W2022081023 title "Translocations Among Antibody Genes in Human Cancer" @default.
• W2022081023 cites W134369158 @default.
• W2022081023 cites W1589276372 @default.
• W2022081023 cites W1966138404 @default.
• W2022081023 cites W1966730043 @default.
• W2022081023 cites W1967072335 @default.
• W2022081023 cites W1969578383 @default.
• W2022081023 cites W1970901330 @default.
• W2022081023 cites W1971112193 @default.
• W2022081023 cites W1978001540 @default.
• W2022081023 cites W1981783129 @default.
• W2022081023 cites W1987600685 @default.
• W2022081023 cites W2001831532 @default.
• W2022081023 cites W2002397775 @default.
• W2022081023 cites W2012850212 @default.
• W2022081023 cites W2013973825 @default.
• W2022081023 cites W2021528730 @default.
• W2022081023 cites W2032772888 @default.
• W2022081023 cites W2038218774 @default.
• W2022081023 cites W2042708086 @default.
• W2022081023 cites W2044083856 @default.
• W2022081023 cites W2047237671 @default.
• W2022081023 cites W2048324748 @default.
• W2022081023 cites W2053572117 @default.
• W2022081023 cites W2054073262 @default.
• W2022081023 cites W2057159445 @default.
• W2022081023 cites W2064735501 @default.
• W2022081023 cites W2068817943 @default.
• W2022081023 cites W2069637913 @default.
• W2022081023 cites W2072392608 @default.
• W2022081023 cites W2082534786 @default.
• W2022081023 cites W2082826626 @default.
• W2022081023 cites W2084210845 @default.
• W2022081023 cites W2085214231 @default.
• W2022081023 cites W2091810736 @default.
• W2022081023 cites W2092299362 @default.
• W2022081023 cites W2094442095 @default.
• W2022081023 cites W2095425146 @default.
• W2022081023 cites W2128856125 @default.
• W2022081023 cites W2169602350 @default.
• W2022081023 cites W2198686154 @default.
• W2022081023 cites W1974596630 @default.
• W2022081023 doi "https://doi.org/10.1126/science.6356357" @default.
• W2022081023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6356357" @default.
• W2022081023 hasPublicationYear "1983" @default.
• W2022081023 type Work @default.
• W2022081023 sameAs 2022081023 @default.
• W2022081023 citedByCount "706" @default.
• W2022081023 countsByYear W20220810232012 @default.
• W2022081023 countsByYear W20220810232013 @default.
• W2022081023 countsByYear W20220810232014 @default.
• W2022081023 countsByYear W20220810232015 @default.
• W2022081023 countsByYear W20220810232016 @default.
• W2022081023 countsByYear W20220810232017 @default.
• W2022081023 countsByYear W20220810232019 @default.
• W2022081023 countsByYear W20220810232020 @default.
• W2022081023 countsByYear W20220810232021 @default.
• W2022081023 countsByYear W20220810232022 @default.
• W2022081023 crossrefType "journal-article" @default.
• W2022081023 hasAuthorship W2022081023A5010721531 @default.
• W2022081023 hasAuthorship W2022081023A5050156267 @default.
• W2022081023 hasAuthorship W2022081023A5054037083 @default.
• W2022081023 hasAuthorship W2022081023A5070752173 @default.
• W2022081023 hasAuthorship W2022081023A5075534723 @default.
• W2022081023 hasAuthorship W2022081023A5078971738 @default.
• W2022081023 hasAuthorship W2022081023A5080451187 @default.
• W2022081023 hasAuthorship W2022081023A5085778554 @default.
• W2022081023 hasConcept C101762097 @default.
• W2022081023 hasConcept C104317684 @default.
• W2022081023 hasConcept C111936080 @default.
• W2022081023 hasConcept C138626823 @default.
• W2022081023 hasConcept C150194340 @default.
• W2022081023 hasConcept C165864922 @default.
• W2022081023 hasConcept C3020196193 @default.
• W2022081023 hasConcept C36823959 @default.
• W2022081023 hasConcept C54355233 @default.
• W2022081023 hasConcept C86803240 @default.
• W2022081023 hasConceptScore W2022081023C101762097 @default.
• W2022081023 hasConceptScore W2022081023C104317684 @default.
• W2022081023 hasConceptScore W2022081023C111936080 @default.
• W2022081023 hasConceptScore W2022081023C138626823 @default.
• W2022081023 hasConceptScore W2022081023C150194340 @default.
• W2022081023 hasConceptScore W2022081023C165864922 @default.
• W2022081023 hasConceptScore W2022081023C3020196193 @default.
• W2022081023 hasConceptScore W2022081023C36823959 @default.
• W2022081023 hasConceptScore W2022081023C54355233 @default.

• next