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• W2022083071 abstract "Prostate cancer (PC) is a leading cause of fatal cancer in men in developed countries. Coeliac disease (CD) has previously been linked to a raised cancer risk, and changes in some exposures following a CD diagnosis might hypothetically raise PC risk.We identified 10,995 patients with CD who had undergone a small intestinal biopsy in 1969-2007. Statistics Sweden then identified 54,233 age-matched male reference individuals from the general population. PC data were obtained from the Swedish Cancer Register. Hazard ratios (HRs) for PC were estimated using Cox regression analysis.During follow-up, 185 individuals with CD (expected n=200) had an incident diagnosis of PC. This corresponds to a HR of 0.92 (0.79-1.08) (with 95% confidence interval) and an absolute risk reduction of 15/100,000 person-years among those with CD. An increased risk was not observed even when identification of PC began 5 years after biopsy.Our conclusion is that a CD diagnosis does not represent an increased risk for PC." @default.
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• W2022083071 date "2011-12-01" @default.
• W2022083071 modified "2023-10-06" @default.
• W2022083071 title "Risk of prostate cancer in a population-based cohort of men with coeliac disease" @default.
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• W2022083071 doi "https://doi.org/10.1038/bjc.2011.536" @default.
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