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• W2022090382 abstract "British Journal of Pharmacology and ChemotherapyVolume 25, Issue 3 p. 577-591 Free Access COMPARISON OF SOME PROPERTIES OF PRONETHALOL AND PROPRANOLOL J. W. BLACK, J. W. BLACK Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, Cheshire Smith Kline & French Limited, Welwyn Garden City, Herts.Search for more papers by this authorW. A. M. DUNCAN, W. A. M. DUNCAN Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, Cheshire Smith Kline & French Limited, Welwyn Garden City, Herts.Search for more papers by this authorR. G. SHANKS, R. G. SHANKS Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, CheshireSearch for more papers by this author J. W. BLACK, J. W. BLACK Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, Cheshire Smith Kline & French Limited, Welwyn Garden City, Herts.Search for more papers by this authorW. A. M. DUNCAN, W. A. M. DUNCAN Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, Cheshire Smith Kline & French Limited, Welwyn Garden City, Herts.Search for more papers by this authorR. G. SHANKS, R. G. SHANKS Imperial Chemical Industries Ltd., Pharmaceuticals Division, Research Department, Alderley Park, Macclesfield, CheshireSearch for more papers by this author First published: December 1965 https://doi.org/10.1111/j.1476-5381.1965.tb01782.xCitations: 141 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES Abboud, F. M., Eckstein, J. W. & Zimmerman, B. G. (1963). Effect of “beta-receptor-blocking drugs” on venous and arterial responses to isoproterenol. Clin. Res., 11, 162. Ahlquist, R. P. (1948). A study of the adrenotropic receptors. Amer. J. Physiol., 153, 586– 600. Ahlquist, R. P. (1963). Beta adrenergic receptor blockade by naphthylisoproterenol. Fed. Proc., 22, 449. Alcock, S. J., Baker, S. B. de C. & Tucker, M. J. (1965). A comparison of the carcinogenicity of pronethalol and propranolol in mice. Brit. med. J., in the press. Alcock, S. J. & Bond, P. A. (1964). Observations on the toxicity of Alderlin (pronethalol) in laboratory animals. Proc. Europ. Soc. Stud. Drug Toxicity, 4, 30– 39. Alleyne, G. A. O., Dickinson, C. J., Dornhorst, A. C., Fulton, R. M., Green, K. G., Hill, I. D., Hurst, P., Laurence, D. R., Pilkington, T., Prichard, B. N. C., Robinson, B. & Rosenheim, M. L. (1963). Effect of pronethalol in angina pectoris. Brit. med. J., ii, 1226– 1229. Apthorp, G. H., Chamberlain, D. A. & Hayward, G. W. (1964). The effects of sympathectomy on the electrocardiogram and effort tolerance in angina pectoris. Brit. Heart J., 26, 218– 226. Barrett, A. M. (1965). 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Naunyn-Schmiedeberg's Arch. exp. Path. Pharmaka., 246, 47– 48. Erlij, D. & Mendez, R. (1964). The modification of digitalis intoxication by excluding adrenergic influences on the heart. J. Pharmacol, exp. Ther., 144, 97– 103. Furchgott, R. F. (1959). The receptors for epinephrine and norepinephrine. Pharmacol. Rev., 11, 429– 442. Grandjean, T. & Rivier, J.-L. (1963). Utilisation d'un antagoniste des catecholamines (I.C.I. 38,174, “Alderlin”) dans le traitement de quelques cas de troubles du rythme cardiaque. Schweiz, med. Wschr., 93, 1101– 1104. Harrison, D. C., Braunwald, E., Glick, G., Mason, D. T., Chidsey, C. A. & Ross, J. (1964). Effect of beta adrenergic blockade on the circulation with particular reference to observations in patients with hypertrophic subaortic stenosis. Circulation, 29, 84– 98. Hess, J. M. & Hampton, L. J. (1964). Prevention of epinephrine-halothane arrhythmias by adrenergic β-receptor blockade. Anesthesiology, 25, 101– 102. Howe, R. (1963). Structure activity relationships of some β-adrenergic blocking agents. Biochem. Pharmacol., 12, suppl. 85. James, T. N. & Nadeau, R. A. (1964). The chronotropic and vagal-blocking actions of naphthylisoproterenol studied by direct perfusion of the sinus node. J. Pharmacol, exp. Ther., 143, 350– 355. Johnstone, M. (1964). Beta-adrenergic blockade with pronethalol during anaesthesia. Brit. J. Anaesth., 36, 224– 232. Kako, K., Krayenbühl, H. P., Lüthy, E. & Hegglin, R. (1964). Cardiovascular effects of catecholamines in dogs before and after β-adrenergic blockade. Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak., 246, 297– 308. Levy, B. & Tozzi, S. (1963). The adrenergic receptive mechanism of the rat uterus. J. Pharmacol, exp. Ther., 142, 178– 184. Lowe, R. D. & Robinson, B. F. (1964). Effect of differential adrenergic blockade on response of forearm blood flow to infused catecholamines. Clin. Sci., 26, 81– 87. Lum, B. K. B. & Kermani, M. H. (1963). Selective loss of response to alpha adrenergic agents following cold storage of the rabbit jejunum. Fed. Proc., 22, 449. McEwen, L. M. (1956). The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain. J. Physiol. (Lond.), 131, 678– 689. Meester, W. D., Hardman, H. F. & Barboriak, J. J. (1963). Quantitative evaluation of nethalide (NET), dichloroisoproterenol (DCI) and N-isopropylmethoxamine (1PM) as beta-receptor blocking agents in the isolated rabbit heart. Pharmacologist, 5, 249. Murray, W. J., McKnight, R. L. & Davis, D. A. (1963). Antagonism of hydrocarbon anaesthetic-epinephrine arrhythmias in dogs by nethalide, a dichloroisoproterenol analogue. Proc. Soc. exp. Biol. (N.Y.), 113, 439– 441. Nagasaka, M., Schaepdryver, A. F. de & Heymans, C. (1964). The anti-adrenergic property of nethalide on the isolated guinea-pig lung. Arch. int. Pharmacodyn., 149, 232– 236. Orlans, F. B. H., Finger, K. F. & Brodie, B. B. (1960). Pharmacological consequences of the selective release of peripheral norepinephrine by syrosingopine (SU 3118). J. Pharmacol, exp. Ther., 128. 131– 139. Paget, G. E. (1963). Carcinogenic action of pronethalol. Brit. med. J., ii, 1266– 1267. Payne, J. P. & Senfield, R. M. (1964). Pronethalol in treatment of ventricular arrhythmias. Brit. med. J., i, 603– 604. Schild, H. O. (1947). A new scale for the measurement of drug antagonism. Brit. J. Pharmacol., 2, 189– 206. Schröder, G. & Werkö, L. (1964). Nethalide, a beta adrenergic blocking agent. Clin. Pharmacol. Ther., 5, 159– 173. Somani, P., Hardman, H. F. & Lum, B. K. B. (1963). Antagonism of cardiac arrhythmias by nethalide. Pharmacologist, 5, 260. Stock, J. P. P. & Dale, N. (1963). Beta-adrenergic receptor blockade in cardiac arrhythmias. Brit med. J., ii, 1230– 1233. Subbu, V. S. V., Flacke, W. & Seifen, E. (1964). Adrenergic and β-blocking action of nethalide. Pharmacologist, 6, 165. Williams, E. M. Vaughan & Sekiya, A. (1963). Prevention of arrhythmias due to cardiac glycosides by block of sympathetic β-receptors. Lancet, i, 420– 421. Citing Literature Volume25, Issue3December 1965Pages 577-591 ReferencesRelatedInformation" @default.
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