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• W2022104449 startingPage "1140" @default.
• W2022104449 abstract "A variety of genetic, mechano-response-related, endocrine-metabolic, and nutritional determinants impact bone health. Among the nutritional influences, protein intake and dietary acid load are two of the factors most controversially discussed. Although in the past high protein intake was often assumed to exert a primarily detrimental impact on bone mass and skeletal health, the majority of recent studies indicates the opposite and suggests a bone-anabolic influence. Studies examining the influence of alkalizing diets or alkalizing supplement provision on skeletal outcomes are less consistent, which raises doubts about the role of acid–base status in bone health. The present review critically evaluates relevant key issues such as acid–base terminology, influencing factors of intestinal calcium absorption, calcium balance, the endocrine-metabolic milieu related to metabolic acidosis, and some methodological aspects of dietary exposure and bone outcome examinations. It becomes apparent that for an adequate identification and characterization of either dietary acid load's or protein's impact on bone, the combined assessment of both nutritional influences is necessary." @default.
• W2022104449 created "2016-06-24" @default.
• W2022104449 creator A5039753818 @default.
• W2022104449 creator A5055538560 @default.
• W2022104449 creator A5073666371 @default.
• W2022104449 date "2014-01-01" @default.
• W2022104449 modified "2023-10-13" @default.
• W2022104449 title "Dietary Protein's and Dietary Acid Load's Influence on Bone Health" @default.
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• W2022104449 doi "https://doi.org/10.1080/10408398.2011.627519" @default.
• W2022104449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24499146" @default.
• W2022104449 hasPublicationYear "2014" @default.
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