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- W2022105630 endingPage "16979" @default.
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- W2022105630 abstract "The six-layered neocortex is a uniquely mammalian structure with evolutionary origins that remain in dispute. One long-standing hypothesis, based on similarities in neuronal connectivity, proposes that homologs of the layer 4 input and layer 5 output neurons of neocortex are present in the avian forebrain, where they contribute to specific nuclei rather than to layers. We devised a molecular test of this hypothesis based on layer-specific gene expression that is shared across rodent and carnivore neocortex. Our findings establish that the layer 4 input and the layer 5 output cell types are conserved across the amniotes, but are organized into very different architectures, forming nuclei in birds, cortical areas in reptiles, and cortical layers in mammals." @default.
- W2022105630 created "2016-06-24" @default.
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- W2022105630 date "2012-10-01" @default.
- W2022105630 modified "2023-10-11" @default.
- W2022105630 title "Cell-type homologies and the origins of the neocortex" @default.
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- W2022105630 doi "https://doi.org/10.1073/pnas.1204773109" @default.
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