FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022108648> ?p ?o ?g. }

• W2022108648 endingPage "708" @default.
• W2022108648 startingPage "700" @default.
• W2022108648 abstract "Urinary calprotectin has recently been identified as a promising biomarker for the differentiation of pre-renal and intrinsic acute kidney injury (AKI). This study compares the diagnostic performance of calprotectin and neutrophil gelatinase-associated lipocalin (NGAL) in this differential diagnosis.Urinary calprotectin and NGAL concentrations were assessed in a study population of 87 subjects including 38 cases of intrinsic AKI, 24 cases of pre-renal AKI and 25 healthy controls. Urinary tract obstruction, renal transplantation and metastatic cancer were defined as exclusion criteria.Mean calprotectin concentrations were significantly lower in pre-renal (190.2 ± 205.7 ng mL(-1) ) than in intrinsic AKI (6250.1 ± 7167.2 ng mL(-1) , P < 0.001). Receiver-operating characteristic (ROC) analysis provided an AUC of 0.99. Mean NGAL concentrations were significantly higher in intrinsic than in pre-renal AKI as well (458.1 ± 695.3 vs. 64.8 ± 62.1 ng mL(-1) , P = 0.001) providing an AUC of 0.82. A combination of the present study population with the cohort of the proof of concept study led to a population of 188 subjects (58 pre-renal AKI, 90 intrinsic AKI, 40 healthy controls). ROC analyses provided an AUC of 0.97 for calprotectin and 0.76 for NGAL yielding sensitivity and specificity values of 93.3 and 94.8% (calprotectin) vs. 75.3 and 72.4% (NGAL). Optimal cut-off values were 440 ng mL(-1) (calprotectin) and 52 ng mL(-1) (NGAL). Pyuria increased calprotectin concentrations independent of renal failure.This study shows that both calprotectin and NGAL are able to differentiate between pre-renal and intrinsic AKI after exclusion of pyuria. In the present population, calprotectin presents a higher sensitivity and specificity than NGAL." @default.
• W2022108648 created "2016-06-24" @default.
• W2022108648 creator A5003787204 @default.
• W2022108648 creator A5006341566 @default.
• W2022108648 creator A5014886153 @default.
• W2022108648 creator A5024882735 @default.
• W2022108648 creator A5048155216 @default.
• W2022108648 creator A5054593137 @default.
• W2022108648 creator A5058860301 @default.
• W2022108648 creator A5060801460 @default.
• W2022108648 creator A5085792074 @default.
• W2022108648 date "2013-02-14" @default.
• W2022108648 modified "2023-10-01" @default.
• W2022108648 title "Calprotectin and neutrophil gelatinase-associated lipocalin in the differentiation of pre-renal and intrinsic acute kidney injury" @default.
• W2022108648 cites W119935841 @default.
• W2022108648 cites W1964405385 @default.
• W2022108648 cites W1967300023 @default.
• W2022108648 cites W1994455716 @default.
• W2022108648 cites W1999084037 @default.
• W2022108648 cites W2001978569 @default.
• W2022108648 cites W2006108883 @default.
• W2022108648 cites W2026291621 @default.
• W2022108648 cites W2031515819 @default.
• W2022108648 cites W2043123870 @default.
• W2022108648 cites W2054244986 @default.
• W2022108648 cites W2057368294 @default.
• W2022108648 cites W2085027200 @default.
• W2022108648 cites W2107159605 @default.
• W2022108648 cites W2108153267 @default.
• W2022108648 cites W2113887559 @default.
• W2022108648 cites W2122264162 @default.
• W2022108648 cites W2138470214 @default.
• W2022108648 cites W2142832537 @default.
• W2022108648 cites W2145648359 @default.
• W2022108648 cites W2157105773 @default.
• W2022108648 cites W2157657209 @default.
• W2022108648 cites W2168294269 @default.
• W2022108648 doi "https://doi.org/10.1111/apha.12064" @default.
• W2022108648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23336369" @default.
• W2022108648 hasPublicationYear "2013" @default.
• W2022108648 type Work @default.
• W2022108648 sameAs 2022108648 @default.
• W2022108648 citedByCount "51" @default.
• W2022108648 countsByYear W20221086482013 @default.
• W2022108648 countsByYear W20221086482014 @default.
• W2022108648 countsByYear W20221086482015 @default.
• W2022108648 countsByYear W20221086482016 @default.
• W2022108648 countsByYear W20221086482017 @default.
• W2022108648 countsByYear W20221086482018 @default.
• W2022108648 countsByYear W20221086482019 @default.
• W2022108648 countsByYear W20221086482020 @default.
• W2022108648 countsByYear W20221086482021 @default.
• W2022108648 countsByYear W20221086482022 @default.
• W2022108648 countsByYear W20221086482023 @default.
• W2022108648 crossrefType "journal-article" @default.
• W2022108648 hasAuthorship W2022108648A5003787204 @default.
• W2022108648 hasAuthorship W2022108648A5006341566 @default.
• W2022108648 hasAuthorship W2022108648A5014886153 @default.
• W2022108648 hasAuthorship W2022108648A5024882735 @default.
• W2022108648 hasAuthorship W2022108648A5048155216 @default.
• W2022108648 hasAuthorship W2022108648A5054593137 @default.
• W2022108648 hasAuthorship W2022108648A5058860301 @default.
• W2022108648 hasAuthorship W2022108648A5060801460 @default.
• W2022108648 hasAuthorship W2022108648A5085792074 @default.
• W2022108648 hasConcept C126322002 @default.
• W2022108648 hasConcept C126894567 @default.
• W2022108648 hasConcept C159641895 @default.
• W2022108648 hasConcept C185592680 @default.
• W2022108648 hasConcept C20299238 @default.
• W2022108648 hasConcept C2778260677 @default.
• W2022108648 hasConcept C2778292693 @default.
• W2022108648 hasConcept C2779134260 @default.
• W2022108648 hasConcept C2780472472 @default.
• W2022108648 hasConcept C2781197716 @default.
• W2022108648 hasConcept C2908647359 @default.
• W2022108648 hasConcept C55493867 @default.
• W2022108648 hasConcept C58471807 @default.
• W2022108648 hasConcept C71924100 @default.
• W2022108648 hasConcept C76318530 @default.
• W2022108648 hasConcept C77411442 @default.
• W2022108648 hasConcept C90924648 @default.
• W2022108648 hasConcept C99454951 @default.
• W2022108648 hasConceptScore W2022108648C126322002 @default.
• W2022108648 hasConceptScore W2022108648C126894567 @default.
• W2022108648 hasConceptScore W2022108648C159641895 @default.
• W2022108648 hasConceptScore W2022108648C185592680 @default.
• W2022108648 hasConceptScore W2022108648C20299238 @default.
• W2022108648 hasConceptScore W2022108648C2778260677 @default.
• W2022108648 hasConceptScore W2022108648C2778292693 @default.
• W2022108648 hasConceptScore W2022108648C2779134260 @default.
• W2022108648 hasConceptScore W2022108648C2780472472 @default.
• W2022108648 hasConceptScore W2022108648C2781197716 @default.
• W2022108648 hasConceptScore W2022108648C2908647359 @default.
• W2022108648 hasConceptScore W2022108648C55493867 @default.
• W2022108648 hasConceptScore W2022108648C58471807 @default.
• W2022108648 hasConceptScore W2022108648C71924100 @default.
• W2022108648 hasConceptScore W2022108648C76318530 @default.
• W2022108648 hasConceptScore W2022108648C77411442 @default.

• next