Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022109495> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2022109495 endingPage "1982" @default.
- W2022109495 startingPage "1980" @default.
- W2022109495 abstract "Antiplatelet agents are a cornerstone in the prevention of secondary stroke, but existing drugs reduce the vascular risk by only a quarter compared with that obtained with placebo, and are associated with bleeding complications, gastrointestinal problems, and potential drug resistance. 1 Antithrombotic Trialists' CollaborationCollaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ. 2002; 324: 71-86 Crossref PubMed Google Scholar As a result, antiplatelet therapies with potentially more favourable risk–benefit ratios are actively being sought. Previous promising animal and human data have suggested that the antiplatelet activity of terutroban (an oral selective antagonist of thromboxane-prostaglandin receptors) was similar to that of aspirin, with additional beneficial pleiotropic vascular effects. Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trialThe trial did not meet the predefined criteria for non-inferiority, but showed similar rates of the primary endpoint with terutroban and aspirin, without safety advantages for terutroban. In a worldwide perspective, aspirin remains the gold standard antiplatelet drug for secondary stroke prevention in view of its efficacy, tolerance, and cost. Full-Text PDF" @default.
- W2022109495 created "2016-06-24" @default.
- W2022109495 creator A5045080146 @default.
- W2022109495 creator A5061938016 @default.
- W2022109495 date "2011-06-01" @default.
- W2022109495 modified "2023-09-24" @default.
- W2022109495 title "Vascular events after stroke: terutroban fails to PERFORM" @default.
- W2022109495 cites W10734288 @default.
- W2022109495 cites W1704466199 @default.
- W2022109495 cites W1971442835 @default.
- W2022109495 cites W1984799285 @default.
- W2022109495 cites W2024352468 @default.
- W2022109495 cites W2090899812 @default.
- W2022109495 cites W2099395511 @default.
- W2022109495 cites W2099884864 @default.
- W2022109495 cites W2120544643 @default.
- W2022109495 cites W2151865549 @default.
- W2022109495 cites W2318352361 @default.
- W2022109495 cites W311320695 @default.
- W2022109495 doi "https://doi.org/10.1016/s0140-6736(11)60708-3" @default.
- W2022109495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21616526" @default.
- W2022109495 hasPublicationYear "2011" @default.
- W2022109495 type Work @default.
- W2022109495 sameAs 2022109495 @default.
- W2022109495 citedByCount "10" @default.
- W2022109495 countsByYear W20221094952013 @default.
- W2022109495 countsByYear W20221094952014 @default.
- W2022109495 countsByYear W20221094952016 @default.
- W2022109495 countsByYear W20221094952018 @default.
- W2022109495 countsByYear W20221094952022 @default.
- W2022109495 crossrefType "journal-article" @default.
- W2022109495 hasAuthorship W2022109495A5045080146 @default.
- W2022109495 hasAuthorship W2022109495A5061938016 @default.
- W2022109495 hasConcept C126322002 @default.
- W2022109495 hasConcept C127413603 @default.
- W2022109495 hasConcept C142724271 @default.
- W2022109495 hasConcept C177713679 @default.
- W2022109495 hasConcept C203092338 @default.
- W2022109495 hasConcept C204787440 @default.
- W2022109495 hasConcept C27081682 @default.
- W2022109495 hasConcept C2776785769 @default.
- W2022109495 hasConcept C2777015399 @default.
- W2022109495 hasConcept C2777265216 @default.
- W2022109495 hasConcept C2777628954 @default.
- W2022109495 hasConcept C2777849778 @default.
- W2022109495 hasConcept C2780645631 @default.
- W2022109495 hasConcept C2909112448 @default.
- W2022109495 hasConcept C2909817843 @default.
- W2022109495 hasConcept C500558357 @default.
- W2022109495 hasConcept C535046627 @default.
- W2022109495 hasConcept C71924100 @default.
- W2022109495 hasConcept C78519656 @default.
- W2022109495 hasConcept C89560881 @default.
- W2022109495 hasConceptScore W2022109495C126322002 @default.
- W2022109495 hasConceptScore W2022109495C127413603 @default.
- W2022109495 hasConceptScore W2022109495C142724271 @default.
- W2022109495 hasConceptScore W2022109495C177713679 @default.
- W2022109495 hasConceptScore W2022109495C203092338 @default.
- W2022109495 hasConceptScore W2022109495C204787440 @default.
- W2022109495 hasConceptScore W2022109495C27081682 @default.
- W2022109495 hasConceptScore W2022109495C2776785769 @default.
- W2022109495 hasConceptScore W2022109495C2777015399 @default.
- W2022109495 hasConceptScore W2022109495C2777265216 @default.
- W2022109495 hasConceptScore W2022109495C2777628954 @default.
- W2022109495 hasConceptScore W2022109495C2777849778 @default.
- W2022109495 hasConceptScore W2022109495C2780645631 @default.
- W2022109495 hasConceptScore W2022109495C2909112448 @default.
- W2022109495 hasConceptScore W2022109495C2909817843 @default.
- W2022109495 hasConceptScore W2022109495C500558357 @default.
- W2022109495 hasConceptScore W2022109495C535046627 @default.
- W2022109495 hasConceptScore W2022109495C71924100 @default.
- W2022109495 hasConceptScore W2022109495C78519656 @default.
- W2022109495 hasConceptScore W2022109495C89560881 @default.
- W2022109495 hasIssue "9782" @default.
- W2022109495 hasLocation W20221094951 @default.
- W2022109495 hasLocation W20221094952 @default.
- W2022109495 hasOpenAccess W2022109495 @default.
- W2022109495 hasPrimaryLocation W20221094951 @default.
- W2022109495 hasRelatedWork W1974609923 @default.
- W2022109495 hasRelatedWork W1998452547 @default.
- W2022109495 hasRelatedWork W2051233830 @default.
- W2022109495 hasRelatedWork W2080539874 @default.
- W2022109495 hasRelatedWork W2124159988 @default.
- W2022109495 hasRelatedWork W2135351822 @default.
- W2022109495 hasRelatedWork W2412770577 @default.
- W2022109495 hasRelatedWork W2753217352 @default.
- W2022109495 hasRelatedWork W2810872557 @default.
- W2022109495 hasRelatedWork W3137208668 @default.
- W2022109495 hasVolume "377" @default.
- W2022109495 isParatext "false" @default.
- W2022109495 isRetracted "false" @default.
- W2022109495 magId "2022109495" @default.
- W2022109495 workType "article" @default.