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- W2022111021 abstract "To evaluate platelet function in mothers and fetuses/neonates exposed to magnesium sulfate intrapartum.This was a prospective cohort study of mothers and fetuses/neonates exposed to magnesium sulfate intrapartum compared to mothers and fetuses/neonates not exposed. Platelet aggregometry was performed in duplicate on specimens from subjects using two different agonists, ADP and collagen, on a whole blood impedance aggregometer.Specimens were processed from 11 mothers and 10 fetuses/neonates exposed to magnesium and 12 mothers and fetuses/neonates, not exposed. There was no difference in platelet aggregation between the specimens from the mothers who were exposed and mothers not exposed. In the specimens from the fetuses/neonates, there was no difference using collagen as an agonist, but using ADP as an agonist, there was a remarkable difference - 0.0 ohms in the exposed group vs. 3.0 ohms in the unexposed group (p < 0.01).In-utero magnesium sulfate exposure significantly suppresses fetal platelet function." @default.
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- W2022111021 date "2011-07-15" @default.
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- W2022111021 title "The effects of magnesium sulfate on maternal and fetal platelet aggregation" @default.
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- W2022111021 doi "https://doi.org/10.3109/14767058.2011.584087" @default.
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