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• W2022113117 abstract "To evaluate the efficacy and toxicity of a highly immuno- and myelo-suppressive conditioning regimen followed by the infusion of large numbers of T-cell-depleted mismatched haematopoietic stem cells in 43 high-risk acute leukaemia patients.A high rate of engraftment (95%) and no graft-versus-host disease (GvHD) were observed. The 4-year probability of event-free survival was 0.25+/-0.09 for acute myeloid leukaemia and 0.17+/-0.07 for acute lymphoid leukaemia patients.This study shows that the main obstacles limiting the use of mismatched transplants, i.e. GvHD and rejection, were overcome." @default.
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• W2022113117 date "2001-03-01" @default.
• W2022113117 modified "2023-10-07" @default.
• W2022113117 title "Total body irradiation-based regimen in the conditioning of patients submitted to haploidentical stem cell transplantation" @default.
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• W2022113117 doi "https://doi.org/10.1016/s0167-8140(00)00333-9" @default.
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