FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022113282> ?p ?o ?g. }

• W2022113282 endingPage "799" @default.
• W2022113282 startingPage "794" @default.
• W2022113282 abstract "Objectives The optimal timing of pyeloplasty for children diagnosed with ureteropelvic junction obstruction (UPJO) after workup for antenatal hydronephrosis is disputed. We sought to examine the potential costs and clinical outcomes of treatment protocols featuring different indications for pediatric pyeloplasty using Markov models. Methods Cost and outcomes analysis using Markov modeling was performed for three treatment algorithms: medical management, immediate pyeloplasty (during the first year of life), and pyeloplasty after no improvement on imaging. The costs were determined from the perspective of the medical institution. The variables tracked during Markov model simulation included age at resolution of UPJO, the proportion of patients with worsened hydronephrosis, the number of pyeloplasties, the number of pyelonephritis episodes, and costs. Sensitivity analyses were performed to determine which elements affected the model and to determine threshold values. Results Immediate pyeloplasty and pyeloplasty after no improvement on imaging resulted in rapid resolution of UPJO (mean age at resolution younger than 2 years) with lower rates of worsened hydronephrosis and pyelonephritis compared with observation alone. For the surgical protocols, the costs per resolved case of UPJO were greater than those for medical management alone at the probability values tested in the Markov models. The sensitivity analysis of all variables over realistic ranges demonstrated that the costs of surgery, annual antibiotics and imaging, and the rate of pyelonephritis were critical in determining the costs. Conclusions Pediatric urologists should include practice-specific features such as the costs of surgery, annual antibiotics and imaging, and pyelonephritis rates when considering efficacious, yet less costly, treatment protocols for UPJO. The optimal timing of pyeloplasty for children diagnosed with ureteropelvic junction obstruction (UPJO) after workup for antenatal hydronephrosis is disputed. We sought to examine the potential costs and clinical outcomes of treatment protocols featuring different indications for pediatric pyeloplasty using Markov models. Cost and outcomes analysis using Markov modeling was performed for three treatment algorithms: medical management, immediate pyeloplasty (during the first year of life), and pyeloplasty after no improvement on imaging. The costs were determined from the perspective of the medical institution. The variables tracked during Markov model simulation included age at resolution of UPJO, the proportion of patients with worsened hydronephrosis, the number of pyeloplasties, the number of pyelonephritis episodes, and costs. Sensitivity analyses were performed to determine which elements affected the model and to determine threshold values. Immediate pyeloplasty and pyeloplasty after no improvement on imaging resulted in rapid resolution of UPJO (mean age at resolution younger than 2 years) with lower rates of worsened hydronephrosis and pyelonephritis compared with observation alone. For the surgical protocols, the costs per resolved case of UPJO were greater than those for medical management alone at the probability values tested in the Markov models. The sensitivity analysis of all variables over realistic ranges demonstrated that the costs of surgery, annual antibiotics and imaging, and the rate of pyelonephritis were critical in determining the costs. Pediatric urologists should include practice-specific features such as the costs of surgery, annual antibiotics and imaging, and pyelonephritis rates when considering efficacious, yet less costly, treatment protocols for UPJO." @default.
• W2022113282 created "2016-06-24" @default.
• W2022113282 creator A5006235300 @default.
• W2022113282 creator A5006849587 @default.
• W2022113282 creator A5049635014 @default.
• W2022113282 date "2008-10-01" @default.
• W2022113282 modified "2023-09-24" @default.
• W2022113282 title "Outcomes and Cost Analysis of Pyeloplasty for Antenatally Diagnosed Ureteropelvic Junction Obstruction Using Markov Models" @default.
• W2022113282 cites W1853490128 @default.
• W2022113282 cites W1993391457 @default.
• W2022113282 cites W1997322641 @default.
• W2022113282 cites W2045517772 @default.
• W2022113282 cites W2058371837 @default.
• W2022113282 cites W2075146883 @default.
• W2022113282 cites W2076383529 @default.
• W2022113282 cites W2081722675 @default.
• W2022113282 cites W2087656045 @default.
• W2022113282 cites W2089148058 @default.
• W2022113282 cites W2089980205 @default.
• W2022113282 cites W2092837051 @default.
• W2022113282 cites W2114299628 @default.
• W2022113282 cites W2119065718 @default.
• W2022113282 cites W2130565466 @default.
• W2022113282 cites W2167103927 @default.
• W2022113282 cites W2417229675 @default.
• W2022113282 cites W4302406594 @default.
• W2022113282 cites W4321059243 @default.
• W2022113282 doi "https://doi.org/10.1016/j.urology.2007.12.093" @default.
• W2022113282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18674802" @default.
• W2022113282 hasPublicationYear "2008" @default.
• W2022113282 type Work @default.
• W2022113282 sameAs 2022113282 @default.
• W2022113282 citedByCount "3" @default.
• W2022113282 countsByYear W20221132822015 @default.
• W2022113282 countsByYear W20221132822020 @default.
• W2022113282 crossrefType "journal-article" @default.
• W2022113282 hasAuthorship W2022113282A5006235300 @default.
• W2022113282 hasAuthorship W2022113282A5006849587 @default.
• W2022113282 hasAuthorship W2022113282A5049635014 @default.
• W2022113282 hasConcept C126322002 @default.
• W2022113282 hasConcept C141071460 @default.
• W2022113282 hasConcept C177713679 @default.
• W2022113282 hasConcept C187212893 @default.
• W2022113282 hasConcept C2777626661 @default.
• W2022113282 hasConcept C2779863012 @default.
• W2022113282 hasConcept C2781040948 @default.
• W2022113282 hasConcept C71924100 @default.
• W2022113282 hasConcept C77411442 @default.
• W2022113282 hasConceptScore W2022113282C126322002 @default.
• W2022113282 hasConceptScore W2022113282C141071460 @default.
• W2022113282 hasConceptScore W2022113282C177713679 @default.
• W2022113282 hasConceptScore W2022113282C187212893 @default.
• W2022113282 hasConceptScore W2022113282C2777626661 @default.
• W2022113282 hasConceptScore W2022113282C2779863012 @default.
• W2022113282 hasConceptScore W2022113282C2781040948 @default.
• W2022113282 hasConceptScore W2022113282C71924100 @default.
• W2022113282 hasConceptScore W2022113282C77411442 @default.
• W2022113282 hasIssue "4" @default.
• W2022113282 hasLocation W20221132821 @default.
• W2022113282 hasLocation W20221132822 @default.
• W2022113282 hasOpenAccess W2022113282 @default.
• W2022113282 hasPrimaryLocation W20221132821 @default.
• W2022113282 hasRelatedWork W1840163173 @default.
• W2022113282 hasRelatedWork W2027385748 @default.
• W2022113282 hasRelatedWork W2036574345 @default.
• W2022113282 hasRelatedWork W2088566412 @default.
• W2022113282 hasRelatedWork W2129194407 @default.
• W2022113282 hasRelatedWork W2164219929 @default.
• W2022113282 hasRelatedWork W2367526802 @default.
• W2022113282 hasRelatedWork W2377261020 @default.
• W2022113282 hasRelatedWork W3030769367 @default.
• W2022113282 hasRelatedWork W4235342768 @default.
• W2022113282 hasVolume "72" @default.
• W2022113282 isParatext "false" @default.
• W2022113282 isRetracted "false" @default.
• W2022113282 magId "2022113282" @default.
• W2022113282 workType "article" @default.