FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022115667> ?p ?o ?g. }

• W2022115667 endingPage "300" @default.
• W2022115667 startingPage "291" @default.
• W2022115667 abstract "The previously determined 3D NMR solution structure of cyclophilin-bound cyclosporin A (CsA) was docked onto the X-ray crystal structure of cyclophilin. Intermolecular nuclear Overhauser effects (NOE) between CsA and cyclophilin were used as constraints in a restrained energy minimization to generate a model of the complex which satisfied all the NOE distance constraints. The model shows that the residues 9 to 11 and 1 to 5 of the cyclic CsA molecule are in contact with cyclophilin. Comparing the model of the CsA-cyclophilin complex to the X-ray crystal structure of a complex of cyclophilin with a substrate for peptidyl-proline cis-trans isomerase activity, i.e. the linear tetrapeptide substrate ac-Ala-Ala-Pro-Ala-amc (ac, acetyl; amc, amidomethylcoumarin), one notices that the contacting peptide segments in the two ligands are oriented in opposite directions, and that the side chain of MeVal-11 of CsA superposes rather precisely with the position of the prolyl residue in ac-Ala-Ala-Pro-Ala-amc." @default.
• W2022115667 created "2016-06-24" @default.
• W2022115667 creator A5000254356 @default.
• W2022115667 creator A5011367130 @default.
• W2022115667 creator A5021205482 @default.
• W2022115667 creator A5030618101 @default.
• W2022115667 creator A5034191259 @default.
• W2022115667 creator A5036728793 @default.
• W2022115667 creator A5043184951 @default.
• W2022115667 creator A5059330877 @default.
• W2022115667 date "1992-04-06" @default.
• W2022115667 modified "2023-10-15" @default.
• W2022115667 title "Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data" @default.
• W2022115667 cites W1518065087 @default.
• W2022115667 cites W1590020374 @default.
• W2022115667 cites W1963697925 @default.
• W2022115667 cites W1964087428 @default.
• W2022115667 cites W1965842863 @default.
• W2022115667 cites W1977911529 @default.
• W2022115667 cites W1978502680 @default.
• W2022115667 cites W1978879981 @default.
• W2022115667 cites W1984754431 @default.
• W2022115667 cites W1988868441 @default.
• W2022115667 cites W1990664560 @default.
• W2022115667 cites W2000058866 @default.
• W2022115667 cites W2012124354 @default.
• W2022115667 cites W2024060688 @default.
• W2022115667 cites W2024842574 @default.
• W2022115667 cites W2034824829 @default.
• W2022115667 cites W2047174875 @default.
• W2022115667 cites W2058767324 @default.
• W2022115667 cites W2069030511 @default.
• W2022115667 cites W2076287580 @default.
• W2022115667 cites W2082040139 @default.
• W2022115667 cites W2085556108 @default.
• W2022115667 cites W2154376077 @default.
• W2022115667 cites W2166968222 @default.
• W2022115667 cites W2321853548 @default.
• W2022115667 cites W2495248229 @default.
• W2022115667 cites W2949250147 @default.
• W2022115667 cites W1995137187 @default.
• W2022115667 doi "https://doi.org/10.1016/0014-5793(92)80866-f" @default.
• W2022115667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1555658" @default.
• W2022115667 hasPublicationYear "1992" @default.
• W2022115667 type Work @default.
• W2022115667 sameAs 2022115667 @default.
• W2022115667 citedByCount "99" @default.
• W2022115667 countsByYear W20221156672012 @default.
• W2022115667 countsByYear W20221156672013 @default.
• W2022115667 countsByYear W20221156672017 @default.
• W2022115667 countsByYear W20221156672018 @default.
• W2022115667 countsByYear W20221156672019 @default.
• W2022115667 countsByYear W20221156672020 @default.
• W2022115667 crossrefType "journal-article" @default.
• W2022115667 hasAuthorship W2022115667A5000254356 @default.
• W2022115667 hasAuthorship W2022115667A5011367130 @default.
• W2022115667 hasAuthorship W2022115667A5021205482 @default.
• W2022115667 hasAuthorship W2022115667A5030618101 @default.
• W2022115667 hasAuthorship W2022115667A5034191259 @default.
• W2022115667 hasAuthorship W2022115667A5036728793 @default.
• W2022115667 hasAuthorship W2022115667A5043184951 @default.
• W2022115667 hasAuthorship W2022115667A5059330877 @default.
• W2022115667 hasBestOaLocation W20221156671 @default.
• W2022115667 hasConcept C104317684 @default.
• W2022115667 hasConcept C119851462 @default.
• W2022115667 hasConcept C153911025 @default.
• W2022115667 hasConcept C181199279 @default.
• W2022115667 hasConcept C185592680 @default.
• W2022115667 hasConcept C2776326521 @default.
• W2022115667 hasConcept C2779281246 @default.
• W2022115667 hasConcept C2779564779 @default.
• W2022115667 hasConcept C2779815552 @default.
• W2022115667 hasConcept C2781264208 @default.
• W2022115667 hasConcept C2909439513 @default.
• W2022115667 hasConcept C2910677434 @default.
• W2022115667 hasConcept C515207424 @default.
• W2022115667 hasConcept C55493867 @default.
• W2022115667 hasConcept C66974803 @default.
• W2022115667 hasConcept C71240020 @default.
• W2022115667 hasConcept C8010536 @default.
• W2022115667 hasConcept C86803240 @default.
• W2022115667 hasConceptScore W2022115667C104317684 @default.
• W2022115667 hasConceptScore W2022115667C119851462 @default.
• W2022115667 hasConceptScore W2022115667C153911025 @default.
• W2022115667 hasConceptScore W2022115667C181199279 @default.
• W2022115667 hasConceptScore W2022115667C185592680 @default.
• W2022115667 hasConceptScore W2022115667C2776326521 @default.
• W2022115667 hasConceptScore W2022115667C2779281246 @default.
• W2022115667 hasConceptScore W2022115667C2779564779 @default.
• W2022115667 hasConceptScore W2022115667C2779815552 @default.
• W2022115667 hasConceptScore W2022115667C2781264208 @default.
• W2022115667 hasConceptScore W2022115667C2909439513 @default.
• W2022115667 hasConceptScore W2022115667C2910677434 @default.
• W2022115667 hasConceptScore W2022115667C515207424 @default.
• W2022115667 hasConceptScore W2022115667C55493867 @default.
• W2022115667 hasConceptScore W2022115667C66974803 @default.
• W2022115667 hasConceptScore W2022115667C71240020 @default.
• W2022115667 hasConceptScore W2022115667C8010536 @default.

• next