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• W2022119153 abstract "Pulmonary edema is a problem of major clinical importance resulting from a persistent imbalance between forces that drive water into the airspace of the lung and the biological mechanisms for its removal. Here, we will first review the fundamental mechanisms implicated in the regulation of lung fluid homeostasis, namely, the Starling forces and the respiratory transepithelial sodium transport. Second, we will discuss the contribution of hypoxia to the perturbation of this fine balance and the role of such perturbations in the development of high-altitude pulmonary edema, a disease characterized by a very high morbidity and mortality. Finally, we will review possible interventions aimed to maintain/restore lung fluid homeostasis and their importance for the prevention/treatment of pulmonary edema." @default.
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• W2022119153 date "2010-05-01" @default.
• W2022119153 modified "2023-09-26" @default.
• W2022119153 title "Lung Fluid Movements in Hypoxia" @default.
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• W2022119153 doi "https://doi.org/10.1016/j.pcad.2010.02.005" @default.
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