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- W2022124477 abstract "Electrochemical biosensor based on electric eel acetylcholinesterase (AChE) (EC 3.1.1.7) was performed for assay of nerve agents – tabun, sarin, soman, cyclosarin, and VX. The biosensor used AChE as biorecognition element. The presence of nerve agents was accompanied by a strong inhibition of AChE activity. Enzyme activity is easily measurable by electrochemical oxidation of thiocholine created from acetylthiocholine (ATChCl) by AChE-catalyzed hydrolysis. The tested nerve agents were successfully assayed. The best limits of detection were achieved for sarin (5.88×10−10 M) and VX (8.51×10−10 M) after one-minute assay. The biosensor was found long term stable at low as well as laboratory temperature." @default.
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- W2022124477 date "2009-05-01" @default.
- W2022124477 modified "2023-10-03" @default.
- W2022124477 title "Nerve Agents Assay Using Cholinesterase Based Biosensor" @default.
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- W2022124477 doi "https://doi.org/10.1002/elan.200804528" @default.
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