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- W2022124519 abstract "Captan was given by gavage in a range of doses once daily for 100 days to young male albino rats. The oral LD50 (100 days) ± S. E. M. or daily dose which killed 50 % of rats over this period was found to be 0.92 ± 0.23 g/kg/day. The oral 100-day LD50 index, or oral LD50 (100 days) expressed as a percentage of the acute oral LD50 (1 dose) was 7.3 ± 1.9 which indicated that on chronic administration captan was the most toxic of 12 drugs for which published values of the 100-day LD50 index are available. Signs of toxicity were most evident during the first 3 weeks of daily administration and were due to a severe gastroenteritis, an inflammatory reaction in many organs, and degenerative changes in other organs." @default.
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- W2022124519 date "2009-03-13" @default.
- W2022124519 modified "2023-09-27" @default.
- W2022124519 title "The 100-Day LD50 Index of Captan" @default.
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- W2022124519 doi "https://doi.org/10.1111/j.1600-0773.1971.tb00607.x" @default.
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