FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022124977> ?p ?o ?g. }

• W2022124977 endingPage "430" @default.
• W2022124977 startingPage "422" @default.
• W2022124977 abstract "Aims : Vascular endothelial (VE)‐cadherin, also known as cadherin‐5 and CD144, is an adhesion molecule uniquely expressed in endothelial cells. We hypothesized that VE‐cadherin may be a useful marker for assessing microvessels and angiogenesis in human breast cancer and sought to determine whether a correlation exists between levels of VE‐cadherin, angiogenic markers factor VIII and platelet endothelial cell adhesion molecule (PECAM)‐1 and patient outcome in breast cancer. Methods and results : Frozen sections from breast cancer primary tumours (tumour n = 114, background n = 30) were immunostained with VE‐cadherin, factor VIII and PECAM‐1 antibodies and microvessel number was assessed. RNA was reverse transcribed and analysed by quantitative polymerase chain reaction (Q‐PCR). VE‐cadherin immunostaining showed a significant difference in microvessel number in tumour compared with background. There was no significant difference in the number of microvessels stained with PECAM‐1 or factor VIII; there was increased staining of other structures within the sample and higher general background staining. Q‐PCR revealed elevated levels of VE‐cadherin and PECAM‐1 in tumour samples compared with background tissue and in patients with a poor prognosis, as determined by the Nottingham Prognostic Index. There was no difference in levels with factor VIII. Both VE‐cadherin and PECAM‐1 had significantly reduced expression in lobular compared with ductal carcinomas: there was no difference with factor VIII. Conclusion : Higher levels of angiogenic marker molecules in breast cancer may have an association with poor prognosis in patients. Moreover, VE‐cadherin appears to be a preferable marker for such analysis." @default.
• W2022124977 created "2016-06-24" @default.
• W2022124977 creator A5017993198 @default.
• W2022124977 creator A5021802346 @default.
• W2022124977 creator A5059803359 @default.
• W2022124977 creator A5085688751 @default.
• W2022124977 date "2005-03-23" @default.
• W2022124977 modified "2023-10-15" @default.
• W2022124977 title "Assessing microvessels and angiogenesis in human breast cancer, using VE-cadherin" @default.
• W2022124977 cites W1809398380 @default.
• W2022124977 cites W1977199477 @default.
• W2022124977 cites W1984617850 @default.
• W2022124977 cites W1990173431 @default.
• W2022124977 cites W2021196791 @default.
• W2022124977 cites W2030437923 @default.
• W2022124977 cites W2040711424 @default.
• W2022124977 cites W2049098554 @default.
• W2022124977 cites W2053134592 @default.
• W2022124977 cites W2056318837 @default.
• W2022124977 cites W2057081948 @default.
• W2022124977 cites W2064297621 @default.
• W2022124977 cites W2068561588 @default.
• W2022124977 cites W2073621056 @default.
• W2022124977 cites W2074070420 @default.
• W2022124977 cites W2085180278 @default.
• W2022124977 cites W2092159426 @default.
• W2022124977 cites W2094282537 @default.
• W2022124977 cites W2097923618 @default.
• W2022124977 cites W2099961094 @default.
• W2022124977 cites W2101290420 @default.
• W2022124977 cites W2111279109 @default.
• W2022124977 cites W2117567491 @default.
• W2022124977 cites W2118278618 @default.
• W2022124977 cites W2126281673 @default.
• W2022124977 cites W2163678566 @default.
• W2022124977 cites W2318923108 @default.
• W2022124977 cites W2320808260 @default.
• W2022124977 doi "https://doi.org/10.1111/j.1365-2559.2005.02104.x" @default.
• W2022124977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15810954" @default.
• W2022124977 hasPublicationYear "2005" @default.
• W2022124977 type Work @default.
• W2022124977 sameAs 2022124977 @default.
• W2022124977 citedByCount "27" @default.
• W2022124977 countsByYear W20221249772012 @default.
• W2022124977 countsByYear W20221249772013 @default.
• W2022124977 countsByYear W20221249772014 @default.
• W2022124977 countsByYear W20221249772019 @default.
• W2022124977 countsByYear W20221249772021 @default.
• W2022124977 crossrefType "journal-article" @default.
• W2022124977 hasAuthorship W2022124977A5017993198 @default.
• W2022124977 hasAuthorship W2022124977A5021802346 @default.
• W2022124977 hasAuthorship W2022124977A5059803359 @default.
• W2022124977 hasAuthorship W2022124977A5085688751 @default.
• W2022124977 hasConcept C121608353 @default.
• W2022124977 hasConcept C126322002 @default.
• W2022124977 hasConcept C142724271 @default.
• W2022124977 hasConcept C1491633281 @default.
• W2022124977 hasConcept C149402561 @default.
• W2022124977 hasConcept C204232928 @default.
• W2022124977 hasConcept C2776436680 @default.
• W2022124977 hasConcept C2778271429 @default.
• W2022124977 hasConcept C2778939058 @default.
• W2022124977 hasConcept C2780394083 @default.
• W2022124977 hasConcept C4224716 @default.
• W2022124977 hasConcept C502942594 @default.
• W2022124977 hasConcept C530470458 @default.
• W2022124977 hasConcept C54355233 @default.
• W2022124977 hasConcept C71924100 @default.
• W2022124977 hasConcept C86803240 @default.
• W2022124977 hasConceptScore W2022124977C121608353 @default.
• W2022124977 hasConceptScore W2022124977C126322002 @default.
• W2022124977 hasConceptScore W2022124977C142724271 @default.
• W2022124977 hasConceptScore W2022124977C1491633281 @default.
• W2022124977 hasConceptScore W2022124977C149402561 @default.
• W2022124977 hasConceptScore W2022124977C204232928 @default.
• W2022124977 hasConceptScore W2022124977C2776436680 @default.
• W2022124977 hasConceptScore W2022124977C2778271429 @default.
• W2022124977 hasConceptScore W2022124977C2778939058 @default.
• W2022124977 hasConceptScore W2022124977C2780394083 @default.
• W2022124977 hasConceptScore W2022124977C4224716 @default.
• W2022124977 hasConceptScore W2022124977C502942594 @default.
• W2022124977 hasConceptScore W2022124977C530470458 @default.
• W2022124977 hasConceptScore W2022124977C54355233 @default.
• W2022124977 hasConceptScore W2022124977C71924100 @default.
• W2022124977 hasConceptScore W2022124977C86803240 @default.
• W2022124977 hasIssue "4" @default.
• W2022124977 hasLocation W20221249771 @default.
• W2022124977 hasLocation W20221249772 @default.
• W2022124977 hasOpenAccess W2022124977 @default.
• W2022124977 hasPrimaryLocation W20221249771 @default.
• W2022124977 hasRelatedWork W1970028203 @default.
• W2022124977 hasRelatedWork W1976539995 @default.
• W2022124977 hasRelatedWork W2023173977 @default.
• W2022124977 hasRelatedWork W2363737579 @default.
• W2022124977 hasRelatedWork W2413197985 @default.
• W2022124977 hasRelatedWork W2416896828 @default.
• W2022124977 hasRelatedWork W2724746526 @default.
• W2022124977 hasRelatedWork W2758641198 @default.

• next