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- W2022126670 abstract "This paper describes the synthesis of deuterium-labelled paclitaxel and its hydroxyl metabolite. Paclitaxel labelled with 2H was obtained in four steps using the commercially available [2H5]benzoic chloride as the stable labelled reagent with a 40% overall yield. The hydroxyl metabolite labelled with 2H was prepared starting from deuterium-labelled paclitaxel in six steps with a 42% overall yield based on unrecovered starting material. Copyright © 2011 John Wiley & Sons, Ltd." @default.
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- W2022126670 date "2011-02-17" @default.
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- W2022126670 title "Synthesis of deuterium-labelled paclitaxel and its hydroxyl metabolite" @default.
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