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- W2022131801 abstract "1,5-Anhydro-D-glucitol (1,5-AG) was found to inhibit trehalase and trehalose phosphorylase activities competitively, because of its structural similarity with D-glucose. Trehalase from Nocardia sp., one of the most 1,5-AG-sensitive enzymes, was used in the determination of 1,5-AG concentration, which is a useful marker for the diagnosis of diabetes. A good linear relationship was observed between 1,5-AG concentration in the range of 0.02 to 1.0 mM and the extent of trehalase inhibition by 1,5-AG. The 1,5-AG concentration range could be determined by estimating enzymatically the amount of the reaction product, D-glucose, produced by the trehalase." @default.
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- W2022131801 date "2001-01-01" @default.
- W2022131801 modified "2023-09-27" @default.
- W2022131801 title "Determination of 1,5-Anhydro-d-glucitol on the basis of its inhibitory effect on trehalase activity" @default.
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- W2022131801 doi "https://doi.org/10.1016/s1389-1723(01)80223-1" @default.
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