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- W2022132878 abstract "Interleukin-17 (IL-17A) is a pro-inflammatory cytokine that has recently been implicated in pathogenesis of Langerhans Cell Histiocytosis (LCH), a potentially fatal disease characterized by lesions including CD207+ (langerin +) histiocytes. However, in this study we were unable to identify IL-17A gene expression in Langerhans cell lesions, and plasma levels of IL-17A did not correlate with disease activity. Therefore, this study does not support a central role for IL-17A in LCH pathogenesis." @default.
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- W2022132878 date "2009-05-01" @default.
- W2022132878 modified "2023-10-11" @default.
- W2022132878 title "Interleukin-17A is not expressed by CD207+ cells in Langerhans cell histiocytosis lesions" @default.
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- W2022132878 doi "https://doi.org/10.1038/nm0509-483" @default.
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