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• W2022133055 abstract "Histamine release induced by Staphylococcus aureus was examined in cells obtained by bronchoalveolar lavage (BAL) in non-topic individuals. Approximately half of the individuals responded with mediatior release to the bacterium, and the release was found to be time- and concentration dependent. No difference was found between the patients obtained by who responded and those who did not respond in regard to age, sex, smoker/nonsmoker % recovery of BAL-fluid, total cell count, differential cell counts, histamine content per mast cell, or diagnoses. Also stimulation of the BAL-cells with the calcium-ionophore A23187 resulted in histamine release, S. aureus-induced histamine release from basophils was examined in leukocyte suspensions obtained from the same individuals, and in all experiments release was found. The dose-response curves were similar to those obtained with BAL cells- The bacteria-induced mediator release from superficially lying cells in the airways epithelium might be of importance for the precipitation or exacerbation of bronchial asthma in respiratory tract infections." @default.
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• W2022133055 date "1991-01-01" @default.
• W2022133055 modified "2023-09-25" @default.
• W2022133055 title "Bacteria-induced histamine release from human bronchoalveolar cells and blood leukocytes" @default.
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• W2022133055 doi "https://doi.org/10.1111/j.1398-9995.1991.tb00542.x" @default.
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