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- W2022133651 endingPage "1263" @default.
- W2022133651 startingPage "1243" @default.
- W2022133651 abstract "The β-lactam antibiotics are essential for the treatment of a wide range of human bacterial diseases. However, a class of zinc-dependent hydrolases known as the metallo-β-lactamase (MBL) can confer bacteria with extended spectrum β-lactam resistance. To date, there are no clinically approved MBL inhibitors, making these enzymes a serious threat to human health. In this review, a structural approach is taken to outline some of the more promising MBL inhibitors and shed light on how the resistance conferred by this emerging class of enzymes may be circumvented in the future." @default.
- W2022133651 created "2016-06-24" @default.
- W2022133651 creator A5022292484 @default.
- W2022133651 creator A5056122200 @default.
- W2022133651 date "2013-07-01" @default.
- W2022133651 modified "2023-10-07" @default.
- W2022133651 title "Targeting metallo-β-lactamase enzymes in antibiotic resistance" @default.
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- W2022133651 doi "https://doi.org/10.4155/fmc.13.55" @default.
- W2022133651 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23859206" @default.
- W2022133651 hasPublicationYear "2013" @default.
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