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• W2022134022 endingPage "1059" @default.
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• W2022134022 abstract "가시오가피 잎, 뿌리, 줄기 및 열매의 수용성, 에탄올 및 메탄올 추출물의 생리활성 물질 분석과 항산화 활성(DPPH free radical scavenging 활성, Cu/Fe-환원력, 간 조직 microsome 생체막 및 linoleic acid 과산화지질, Tyrosinase 저해활성)을 측정 하였다. 가시오가피 잎의 열수 추출물에서 추출 수율 16.04%, 폴리페놀 화합물 함량2.67% 및 플라보노이드 함량 1.43%로 가장 높았다. 가시오가피 잎, 뿌리, 줄기 및 열매의 주요 미네랄은 K, Ca 및 Mg 이었다. DPPH free radical scavenging 활성, Cu/Fe-환원력, 간 조직 microsome 생체막 및 linoleic acid의 과산화 지질 측정에 의한 항산화 활성은 가시오가피 잎, 뿌리, 줄기 및 열매 모두에서 나타났으며, 시료 처리 농도 의존적으로 활성이 증가되는 것으로 나타났다. 이상의 실험 결과에서 가시오가피 잎, 뿌리, 줄기 및 열매 모두에서 높은 항산화 활성이 있었으며, 이는 폴리페놀 화합물과 플라보노이드와 같은 생리활성 성분을 많이 함유하고 있는 것과 깊은 관련성이 있는 것으로 향후 건강기능식품이나 기능성화장품의 천연 항산화제 소재 개발 관련 연구의 기초자료로 활용될 수 있을 것으로 사료되어 진다. 【The contents of bioactive and antioxidative activities (DPPH ( ${alpha},{alpha}'$ -diphenyl- ${beta}$ -picrylhydrazyl), free radical scavenging activity, peroxidation of linoleic acid and rat hepatocyte microsome, and Fe/Cu reducing power, tyrosinase inhibition activity) were tested by in vitro experimental models using water, hot water, ethanol and methanol extracts of leaves (ASL), roots (ASR), stems (ASS) and fruits (ASF) from Acanthopanax senticosus. Hot water extract from ASL showed the highest extraction yield (16.04%) as well as highest contents of phenolic compounds (2.67%) and flavonoids (1.43%). Major minerals were K, Ca and Mg. In oxidation in vitro models using DPPH free radical scavenging activity, Fe/Cu reducing power, $Fe^{2+}$ /ascorbate-induced linoleic acid peroxidation by ferric thiocyanate and thiobarbituric acid (TBA) methods, tyrosinase inhibition activity and autooxidation of rat hepatic microsomes membrane, and antioxidative activities were strong in Acanthopanax senticosus. From these results, ASL extracts were shown to have the most potent antioxidative properties and contain the highest amounts of antioxidative compounds such as phenolic compounds and flavonoids. These results may provide the basic data to understand the biological activities of bio-active materials derived from leaves of Acanthopanax senticosus.】" @default.
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• W2022134022 date "2011-07-30" @default.
• W2022134022 modified "2023-10-16" @default.
• W2022134022 title "Antioxidative Activity and Chemical Characteristics of Leaves, Roots, Stems and Fruits Extracts from Acanthopanax senticosus" @default.
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