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- W2022135066 abstract "1. The applications of n.m.r. spectroscopy studies to drug metabolism, both in vitro (biofluids, isolated cells, excised tissue samples, isolated organs) and in vivo (animals, humans) are reviewed. 2. N.m.r. is a relatively insensitive technique, but it has the great advantage of being non-invasive and non-destructive, i.e. it allows a direct study of intact biological samples. 3. The majority of studies examined deal with 19F-n.m.r. spectroscopy mainly because of the favourable n.m.r. characteristics of this nucleus, and the low level of endogenous fluorine which gives no detectable 19F signal. However, the potential utility of 1H-31P- and 13C-n.m.r. is also emphasized." @default.
- W2022135066 created "2016-06-24" @default.
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- W2022135066 date "1989-01-01" @default.
- W2022135066 modified "2023-10-12" @default.
- W2022135066 title "The Application of Nuclear Magnetic Resonance Spectroscopy to Drug Metabolism Studies" @default.
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- W2022135066 doi "https://doi.org/10.3109/00498258909042297" @default.
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