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- W2022136370 abstract "THE PATIENT, a 24-year-old nurse, was first seen on Oct. 2, 1959. She was desirous of breaking her addiction to methyprylon (Noludar), a drug which she had been using for 18 months. During the past year, she reported using a minimum of 25 300-mg. tablets (7,500 mg.) per day. Frequently her intake reached 40 of these tablets (12,000 mg.) per day. She had used barbiturates to excess from 1953 to January, 1958, when, in a self-imposed attempt to terminate her addiction to these materials, she substituted methyprylon. It is significant that she could replace the barbiturates with methyprylon, despite their dissimilar chemistry (see figure). <h3>Report of a Case</h3> The patient's history included a diagnosis of pernicious anemia in 1952 which was confirmed by the presence of achlorhydria. She took vitamin B<sub>12</sub>orally and by injection for a few months, and has had no evidence of anemia or combined-system" @default.
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- W2022136370 date "1961-07-08" @default.
- W2022136370 modified "2023-09-25" @default.
- W2022136370 title "Addiction to Methyprylon" @default.
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- W2022136370 doi "https://doi.org/10.1001/jama.1961.73040270045013" @default.
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