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- W2022140693 abstract "A new variant of a technique for <i>in vivo </i>production of antibodies to various antigens with colloidal-gold nanoparticles as carrier is discussed. With this technique we obtained highly specific and relatively high-titre antibodies to different antigens. The antibodies were tested by an immunodot assay with gold nanoparticle markers. Our results provide the first demonstration that immunization of animals with colloidal gold complexed with either haptens or complete antigens gives rise to highly specific antibodies even without the use of complete Freund's adjuvant. These findings may attest to the adjuvanticity of gold nanoparticles itself. We provide also experimental results and discussion aimed at elucidation of possible mechanisms of the discovered colloidal-gold-adjuvanticity effect." @default.
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- W2022140693 date "2006-06-30" @default.
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- W2022140693 title "<title>The adjuvanticity of gold nanoparticles</title>" @default.
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- W2022140693 doi "https://doi.org/10.1117/12.695006" @default.
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