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- W2022144539 abstract "Prompted by the notion that the membrane channels in gap junctions conduct growth-regulating signals from cell to cell, we transferred the alpha 1 gene for the channel protein (connexin43) of rat heart to tumorigenic mouse MCA-10 cells. Upon incorporation into the cell genome, this exogenous gene was expressed, resulting in functional channels and normal growth regulation: cell-cell communication, determined with a channel-permeant 400-dalton fluorescent tracer, was increased and tumorigenicity, determined in nude mice, was suppressed." @default.
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- W2022144539 date "1993-01-01" @default.
- W2022144539 modified "2023-10-13" @default.
- W2022144539 title "Gap-junction protein gene suppresses tumorigenicity" @default.
- W2022144539 doi "https://doi.org/10.1093/carcin/14.5.1073" @default.
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