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- W2022144962 abstract "Taking on water: The thermodynamics of G-quadruplex–protein binding were investigated for a thrombin-binding DNA aptamer (TBA) and thrombin under the molecular crowding condition of PEG 200. The binding affinity of the TBA–thrombin interaction decreased with a increasing PEG 200 concentration that decreased the water activity. This work suggests that water molecules are taken up during G-quadruplex–protein binding. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2022144962 date "2011-06-10" @default.
- W2022144962 modified "2023-10-18" @default.
- W2022144962 title "Hydration is Required in DNA G-Quadruplex-Protein Binding" @default.
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- W2022144962 doi "https://doi.org/10.1002/cbic.201100264" @default.
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